ArticleMicrobiology (Reading, England)2013
Type 1 and type 2 strains of Mycoplasma pneumoniae form different biofilms.
Article in Microbiology (Reading, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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Who cites it
50 citing papers in PubMed, 81 citations in OpenAlex.
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- Unravelling distinct patterns of metagenomic surveillance and respiratory microbiota between two P1 genotypes ofEmerging microbes & infections · 2025Article
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- Assembly Formation of P65 Protein, Featured by an Intrinsically Disordered Region Involved in Gliding Machinery ofBiomolecules · 2025Article
- A diagnostic host-specific transcriptome response for Mycoplasma pneumoniae pneumonia to guide pediatric patient treatment.Nature communications · 2025Article
- Capsular Polysaccharide Production in Bacteria of the Mycoplasma Genus: A Huge Diversity of Pathways and Synthases for So-Called Minimal Bacteria.Molecular microbiology · 2024Article
- Review
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- Pathogenic avian mycoplasmas show phenotypic differences in their biofilm forming ability compared to non-pathogenic speciesBiofilm · 2024Article
- Computational exploration of the global microbiome for antibiotic discovery.bioRxiv : the preprint server for biology · 2023Article
- The Association betweenMicroorganisms · 2023Article
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- Cell shape controls rheotaxis in small parasitic bacteria.PLoS pathogens · 2022Article
- TheFrontiers in microbiology · 2022Review
- Molecular Tools for TypingFrontiers in microbiology · 2022Review
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- Mycoplasma pneumoniae P1 Genotype Indicates Severity of Lower Respiratory Tract Infections in Children.Journal of clinical microbiology · 2021Article
- Visualisation and biovolume quantification in the characterisation of biofilm formation in Mycoplasma fermentans.Scientific reports · 2021Article
- Review
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Several mycoplasma species have been shown to form biofilms that confer resistance to antimicrobials and which may affect the host immune system, thus making treatment and eradication of the pathogens difficult. The present study shows that the biofilms formed by two strains of the human pathogen Mycoplasma pneumoniae differ quantitatively and qualitatively. Compared with strain UAB PO1, strain M129 grows well but forms biofilms that are less robust, with towers that are less smooth at the margins. A polysaccharide containing N-acetylglucosamine is secreted by M129 into the culture medium but found in tight association with the cells of UAB PO1. The polysaccharide may have a role in biofilm formation, contributing to differences in virulence, chronicity and treatment outcome between strains of M. pneumoniae. The UAB PO1 genome was found to be that of a type 2 strain of M. pneumoniae, whereas M129 is type 1. Examination of other M. pneumoniae isolates suggests that the robustness of the biofilm correlates with the strain type.
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