Evidence map›Paper›PMID 23412747›Full record

ArticleGenetics and molecular biology2012

Plant responses to stresses: Role of ascorbate peroxidase in the antioxidant protection.

Andréia Caverzan, Gisele Passaia, Silvia Barcellos Rosa, Carolina Werner Ribeiro, Fernanda Lazzarotto, Márcia Margis-Pinheiro

Open access · goldAbstract read
In one paragraph

Article in Genetics and molecular biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 238 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
238citing papers in PubMed, 2 pooled it
23.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

238 citing papers in PubMed, 2 syntheses or guidelines pooled it, 763 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Integrated nutrient and plant growth regulator management improves cadmium phytoextraction in Ricinus communis.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Article
  4. Review
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  10. Plants (Basel, Switzerland) · 2026
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  13. Review
  14. Article
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  17. Article
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  20. NeemAzalPlants (Basel, Switzerland) · 2025
    Article

178 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Andréia CaverzanPrograma de Pós-Graduação em Genética e Biologia Molecular, Departamento de Genética, Universidade Federal Rio Grande do Sul, Porto Alegre, RS, Brazil.
Gisele Passaia
Silvia Barcellos Rosa
Carolina Werner Ribeiro
Fernanda Lazzarotto
Márcia Margis-Pinheiro
Universidade Federal do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

When plants are exposed to stressful environmental conditions, the production of Reactive Oxygen Species (ROS) increases and can cause significant damage to the cells. Antioxidant defenses, which can detoxify ROS, are present in plants. A major hydrogen peroxide detoxifying system in plant cells is the ascorbate-glutathione cycle, in which, ascorbate peroxidase (APX) enzymes play a key role catalyzing the conversion of H(2)O(2) into H(2)O, using ascorbate as a specific electron donor. Different APX isoforms are present in distinct subcellular compartments, such as chloroplasts, mitochondria, peroxisome, and cytosol. The expression of APX genes is regulated in response to biotic and abiotic stresses as well as during plant development. The APX responses are directly involved in the protection of plant cells against adverse environmental conditions. Furthermore, mutant plants APX genes showed alterations in growth, physiology and antioxidant metabolism revealing those enzymes involvement in the normal plant development.

Indexed as

abiotic stressantioxidant systemascorbate peroxidasemutant plantsreactive oxygen species

Identifiers

PMID23412747
PMCPMC3571416
OpenAlexW2145725157

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.