Evidence map›Paper›PMID 23412657›Full record

ArticleNucleus (Austin, Tex.)

Regulation and coordination of nuclear envelope and nuclear pore complex assembly.

Michaela Clever, Yasuhiro Mimura, Tomoko Funakoshi, Naoko Imamoto

Abstract read
In one paragraph

Article in Nucleus (Austin, Tex.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Michaela CleverCellular Dynamics Laboratory, RIKEN Advanced Science Institute 2-1 Hirosawa, Wako, Japan.
Yasuhiro Mimura
Tomoko Funakoshi
Naoko Imamoto

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In metazoans with "open" mitosis, cells undergo structural changes involving the complete disassembly of the nuclear envelope (NE). In post-mitosis, the dividing cell faces the difficulty to reassemble NE structures in a highly regulated fashion around separated chromosomes. The de novo formation of nuclear pore complexes (NPCs), which are gateways between the cytoplasm and nucleoplasm across the nuclear membrane, is an archetype of macromolecular assembly and is therefore of special interest. The reformation of a functional NE further involves the reassembly and organization of other NE components, the nuclear membrane and NE proteins, around chromosomes in late mitosis.   Here, we discuss the function of NE components, such as lamins and INM proteins, in NE reformation and highlight recent results on coordination of NPC and NE assembly.

Indexed as

Cell NucleusChromosomesCytoplasmHumansLaminsMitosisNuclear EnvelopeNuclear PoreNuclear Pore Complex ProteinsLaminsNuclear Pore Complex Proteinsinner nuclear membranelaminnuclear envelopenuclear pore complexnuclear reassemblynucleoporinopen mitosis

Identifiers

PMID23412657
PMCPMC3621742

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.