Evidence map›Paper›PMID 23412570›Full record

ReviewMolecular & cellular proteomics : MCP2013

Application of microarrays for deciphering the structure and function of the human glycome.

David F Smith, Richard D Cummings

Open access · hybridAbstract readReview
In one paragraph

Review in Molecular & cellular proteomics : MCP, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 66 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Functional reprogramming ofThe Journal of biological chemistry · 2020
    Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Microbe-focused glycan array screening platform.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Glycointeractions in bacterial pathogenesis.Nature reviews. Microbiology · 2018
    Review
  18. Article
  19. Computational approaches to define a human milk metaglycome.Bioinformatics (Oxford, England) · 2016
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

David F SmithDepartment of Biochemistry and Glycomics Center, Emory University School of Medicine, Atlanta, Georgia 30322, USA. dfsmith@emory.edu
Richard D Cummings
Emory University · US

Funding

Overall Priority Score P41GM103694 · NIGMS · EMORY UNIVERSITY · PI CUMMINGS, RICHARD D · 2013 to 2018
$6.9M
Protein-Glycan Interaction Resource of the CFGR24GM098791 · NIGMS · EMORY UNIVERSITY · PI CUMMINGS, RICHARD D, PAULSON, JAMES C · 2011 to 2013
$2.6M
Shotgun Glycomics: Linking Glycan Structure and FunctionR01GM085448 · NIGMS · EMORY UNIVERSITY · PI SMITH, DAVID FLETCHER · 2008 to 2011
$2.3M
NIGMS NIH HHS GM85448NIGMS NIH HHS GM98791NIGMS NIH HHS P41 GM103694NIGMS NIH HHS R01 GM085448NIGMS NIH HHS R24 GM098791
6 · The paper itself

Abstract

Glycan structures were defined historically using multiple methods to determine composition, sequence, linkage, and anomericity of component monosaccharides. Such approaches have been replaced by more sensitive MS methods to profile or predict glycan structures, but these methods are limited in their ability to completely define glycan structures. Glycan-binding proteins, including lectins and antibodies, have been found to have exquisite binding specificities that can provide information about glycan structures. Here, we show glycan-binding proteins can be used along with MS to help define glycan linkages and other determinants in unknown glycans printed as shotgun glycan microarrays.

Indexed as

AnimalsCarbohydrate ConformationCarbohydrate SequenceGlycomicsHumansMicroarray AnalysisMilk, HumanMolecular Sequence DataPolysaccharidesProtein BindingPolysaccharides

Identifiers

PMID23412570
PMCPMC3617337
OpenAlexW2160600646

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.