ArticleBiomedical optics express2013
Achromatized endomicroscope objective for optical biopsy.
Article in Biomedical optics express, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 29 citations in OpenAlex.
- Hybrid endomicroscopic objective with monolithic multi-material achromatic triplet fabricated using two-photon lithography.Applied optics · 2026Article
- Field curvature reduction in miniaturized high numerical aperture and large field-of-view objective lenses with sub 1 µm lateral resolution.Biomedical optics express · 2023Article
- High-resolution endomicroscopy with a spectrally encoded miniature objective.Biomedical optics express · 2019Article
- Optical design and evaluation of a 4 mm cost-effective ultra-high-definition arthroscope.Biomedical optics express · 2014Article
- Needle-based fluorescence endomicroscopy via structured illumination with a plastic, achromatic objective.Journal of biomedical optics · 2013Article
- Optimizing the performance of dual-axis confocal microscopes via Monte-Carlo scattering simulations and diffraction theory.Journal of biomedical optics · 2013Article
- Fiber bundle endocytoscopy.Biomedical optics express · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Currently, researchers and clinicians lack achromatized endomicroscope objectives that are as narrow as biopsy needles. We present a proof-of-concept prototype that validates the optical design of an NA0.4 objective. The objective, built with plastic lenses, has a 0.9 mm clear aperture and is achromatized from 452 nm to 623 nm. The objective's measured Strehl ratio is 0.74 ± 0.05 across a 250 μm FOV. We perform optical sectioning via structured illumination through the objective while capturing fluorescence images of breast carcinoma cells stained with proflavine and cresyl violet. This technology has the potential to improve optical biopsies and provide the next step forward in cancer diagnostics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.