Evidence map›Paper›PMID 23411422›Full record

ArticleInternational journal of clinical and experimental pathology2013

Study on the clinical significance of Argonaute2 expression in colonic carcinoma by tissue microarray.

Ying-Xin Wang, Xiao-Yan Zhang, Bao-Feng Zhang, Chang-Qing Yang, Heng-Jun Gao

Abstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. MicroRNA Biogenesis Pathway Genes Are Deregulated in Colorectal Cancer.International journal of molecular sciences · 2019
    Article
  2. Article
  3. Article
  4. EIF2C, Dicer, and Drosha are up-regulated along tumor progression and associated with poor prognosis in bladder carcinoma.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2015
    Article
  5. HLJ1 is a novel biomarker for colorectal carcinoma progression and overall patient survival.International journal of clinical and experimental pathology · 2014
    Article
  6. Evaluation of Argonaute protein as a predictive marker for human clear cell renal cell carcinoma.International journal of clinical and experimental pathology · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ying-Xin WangDepartment of Gastroenterology, Tongji University Shanghai, China.
Xiao-Yan Zhang
Bao-Feng Zhang
Chang-Qing Yang
Heng-Jun Gao

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo study the expression levels and clinical significance of Argonaute2 (EIF2C2) on colonic carcinomas and normal tissues.

methodsColon tissue samples from 90 cases of colonic carcinomas and 90 normal subjects were accumulated and made into a tissue microarray containing 360 dots. Expression of Argonaute2 (EIF2C2) was detected by immunohistochemical staining of the tissue microarray.

resultsThere was significant difference in the expression levels of Argonaute2 (EIF2C2) between colonic carcinomas and normal tissues (P<0.01). However, the expression of Argonaute2 (EIF2C2) was not related to sex, age, position, differentiation, lymphatic metastasis and clinical stage of the tumor (P>0.05).

conclusionAbnormal expression of Argonaute2 (EIF2C2) may be correlated with colon tumorigenesis.

Indexed as

AdenocarcinomaAdultAgedAged, 80 and overArgonaute ProteinsColonColonic NeoplasmsFemaleHumansLymphatic MetastasisLymph NodesMaleMiddle AgedNeoplasm StagingRetrospective StudiesTissue Array AnalysisAGO2 protein, humanArgonaute ProteinsArgonaute2colonic carcinomaimmunohistochemstryTissue mircroarray

Identifiers

PMID23411422
PMCPMC3563199

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.