Evidence map›Paper›PMID 23409916›Full record

ArticleAmerican journal of public health2013

Alcohol-attributable cancer deaths and years of potential life lost in the United States.

David E Nelson, Dwayne W Jarman, Jürgen Rehm, Thomas K Greenfield, Grégoire Rey, William C Kerr, Paige Miller, Kevin D Shield, Yu Ye, Timothy S Naimi

Abstract read
In one paragraph

Article in American journal of public health, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
96citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

96 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Aspirin and the Primary Prevention of Cardiovascular Diseases: An Approach Based on Individualized, Integrated Estimation of Risk.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2017
    Guideline
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  8. Loneliness is correlated with cancer mortality in US counties: an ecological analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  9. Inaccessible mental health care is a risk factor for risky drinking behaviors among cancer survivors: an All of Us survey-based cohort study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
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36 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

David E NelsonNational Cancer Institute, Bethesda, MD 20892-7105, USA. nelsonde@mail.nih.gov
Dwayne W Jarman
Jürgen Rehm
Thomas K Greenfield
Grégoire Rey
William C Kerr
Paige Miller
Kevin D Shield
Yu Ye
Timothy S Naimi

Funding

TREND &STRUCTURE OF ALCOHOL DEPENDENCE--GENERAL POPULATION 1990 SURVEY DATAP50AA005595 · NIAAA · WESTERN CONSORTIUM FOR PUBLIC HEALTH · PI MARTINEZ, PRISCILLA · 1985 to 2025
$34.1M
Statistical and Data Services Infrastructure CoreP30AA005595 · NIAAA · PUBLIC HEALTH INSTITUTE · PI KERR, WILLIAM C. · 2006 to 2010
$7.2M
Youth Drinking: The Effects of Alcohol Control Policies and Adult Drinking PatteR01AA018377 · NIAAA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI NAIMI, TIMOTHY SIMONDS · 2009 to 2012
$2.0M
NIAAA NIH HHS P30 AA005595NIAAA NIH HHS P50 AA005595NIAAA NIH HHS R01 AA018377NIAAA NIH HHS R01-AA018377
6 · The paper itself

Abstract

objectivesOur goal was to provide current estimates of alcohol-attributable cancer mortality and years of potential life lost (YPLL) in the United States.

methodsWe used 2 methods to calculate population-attributable fractions. We based relative risks on meta-analyses published since 2000, and adult alcohol consumption on data from the 2009 Alcohol Epidemiologic Data System, 2009 Behavioral Risk Factor Surveillance System, and 2009-2010 National Alcohol Survey.

resultsAlcohol consumption resulted in an estimated 18,200 to 21,300 cancer deaths, or 3.2% to 3.7% of all US cancer deaths. The majority of alcohol-attributable female cancer deaths were from breast cancer (56% to 66%), whereas upper airway and esophageal cancer deaths were more common among men (53% to 71%). Alcohol-attributable cancers resulted in 17.0 to 19.1 YPLL for each death. Daily consumption of up to 20 grams of alcohol (≤ 1.5 drinks) accounted for 26% to 35% of alcohol-attributable cancer deaths.

conclusionsAlcohol remains a major contributor to cancer mortality and YPLL. Higher consumption increases risk but there is no safe threshold for alcohol and cancer risk. Reducing alcohol consumption is an important and underemphasized cancer prevention strategy.

Indexed as

AdultAlcohol DrinkingBreast NeoplasmsEsophageal NeoplasmsFemaleHumansMaleNeoplasmsPopulation SurveillanceRisk FactorsSex FactorsUnited States

Identifiers

PMID23409916
PMCPMC3673233

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.