ArticleAnatomical record (Hoboken, N.J. : 2007)2013
Comparative anatomy of mouse and human nail units.
Article in Anatomical record (Hoboken, N.J. : 2007), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 56 citations in OpenAlex.
- Nail proximal fold stem cells participate in nail growth, orchestrating enhanced digit regeneration via bone morphogenetic protein signaling activation.Stem cells (Dayton, Ohio) · 2026Article
- Transcriptomic landscape around wound bed defines regenerative versus non-regenerative outcomes in mouse digit amputation.PLoS computational biology · 2025Article
- Skin Appendage Proteins of Tetrapods: Building Blocks of Claws, Feathers, Hair and Other Cornified Epithelial Structures.Animals : an open access journal from MDPI · 2025Review
- Convergent Evolution of Cysteine-Rich Keratins in Horny Teeth of Jawless Vertebrates and in Cornified Skin Appendages of Amniotes.Molecular biology and evolution · 2025Article
- Convergent Evolution Has Led to the Loss of Claw Proteins in Snakes and Worm Lizards.Genome biology and evolution · 2025Article
- The development of hair follicles and nail.Developmental biology · 2024Review
- Keratins 6, 16, and 17 in Health and Disease: A Summary of Recent Findings.Current issues in molecular biology · 2024Review
- Coxsackievirus A10 impairs nail regeneration and induces onychomadesis by mimicking DKK1 to attenuate Wnt signaling.The Journal of experimental medicine · 2024Article
- Article
- Witch Nails (Krt90whnl): A spontaneous mouse mutation affecting nail growth and development.PloS one · 2022Article
- The Potential of Nail Mini-Organ Stem Cells in Skin, Nail and Digit Tips Regeneration.International journal of molecular sciences · 2021Review
- Predictive Model of Nail Consistency Using Scanning Electron Microscopy with Energy-Dispersive X-Ray.Biology · 2021Article
- Manual dexterity of mice during food-handling involves the thumb and a set of fast basic movements.PloS one · 2020Article
- Nail abnormalities identified in an ageing study of 30 inbred mouse strains.Experimental dermatology · 2019Article
- The expression of equine keratins K42 and K124 is restricted to the hoof epidermal lamellae of Equus caballus.PloS one · 2019Article
- Macrophages and fibroblasts during inflammation and tissue repair in models of organ regeneration.Regeneration (Oxford, England) · 2017Review
- Epithelium-Derived Wnt Ligands Are Essential for Maintenance of Underlying Digit Bone.The Journal of investigative dermatology · 2016Article
- Ichthyosis with confetti: clinics, molecular genetics and management.Orphanet journal of rare diseases · 2015Review
- Dsp rul: a spontaneous mouse mutation in desmoplakin as a model of Carvajal-Huerta syndrome.Experimental and molecular pathology · 2015Article
- Systematic evaluation of skin and adnexa in mutant laboratory mice.Current protocols in mouse biology · 2014Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Recent studies of mice with hair defects have resulted in major contributions to the understanding of hair disorders. To use mouse models as a tool to study nail diseases, a basic understanding of the similarities and differences between the human and mouse nail unit is required. In this study we compare the human and mouse nail unit at the macroscopic and microscopic level and use immunohistochemistry to determine the keratin expression patterns in the mouse nail unit. Both species have a proximal nail fold, cuticle, nail matrix, nail bed, nail plate, and hyponychium. Distinguishing features are the shape of the nail and the presence of an extended hyponychium in the mouse. Expression patterns of most keratins are similar. These findings indicate that the mouse nail unit shares major characteristics with the human nail unit and overall represents a very similar structure, useful for the investigation of nail diseases and nail biology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.