ArticleBMJ open2013
Thirty-day complications after laparoscopic or open cholecystectomy: a population-based cohort study in Italy.
Article in BMJ open, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 37 citations in OpenAlex.
- Trial
- Prehabilitation: A Catalyst for Transforming Toward Value-Based, Personalized Perioperative Health and Care.Journal of clinical medicine · 2025Article
- Effect of a Laparoscopic Donor Nephrectomy in Healthy Living Kidney Donors on the Acute Phase Response Using Either Propofol or Sevoflurane Anesthesia.International journal of molecular sciences · 2025Article
- The safety of telemedicine clinics as an alternative to in-person preoperative assessment for elective laparoscopic cholecystectomy in patients with benign gallbladder disease: a retrospective cohort study.Patient safety in surgery · 2023Article
- Article
- Differences in risk factors for surgical site infection between laparotomy and laparoscopy in gastrointestinal surgery.PloS one · 2022Article
- Unusual cause of gas complicating a biloma, postcholecystectomy.BMJ case reports · 2021Article
- Novel Technique for Laparoscopic Common Bile Duct Exploration Using Endovascular Instrumentation.Cureus · 2019Article
- Early cross-sectional imaging following open and laparoscopic cholecystectomy: a primer for radiologists.Insights into imaging · 2018Review
- Risk Factors for Surgical Site Infection After Cholecystectomy.Open forum infectious diseases · 2017Article
- Current practices in biliary surgery: Do we practice what we teach?Surgical endoscopy · 2016Article
- Bayesian estimation of the accuracy of ICD-9-CM- and CPT-4-based algorithms to identify cholecystectomy procedures in administrative data without a reference standard.Pharmacoepidemiology and drug safety · 2016Article
- A propensity-score matched comparison of perioperative and early renal functional outcomes of robotic versus open partial nephrectomy.PloS one · 2014Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe objective of the study is to evaluate short-term complications after laparoscopic (LC) or open cholecystectomy (OC) in patients with gallstones by using linked hospital discharge data.
designPopulation-based cohort study.
settingData were obtained from the Regional Hospital Discharge Registry Lazio Region in Central Italy (around 5 million inhabitants) in 2007-2008.
participantsAll patients admitted to hospitals of Lazio with symptomatic gallstones (International Classification of disease, 9th Revision, Clinical Modification (ICD-9-CM)=574) who underwent LC (ICD-9-CM 51.23) or OC (ICD-9-CM 51.22). OUTCOME MEASURES: (1)'30-day surgical-related complications' defined as any complication of the biliary tract (including postoperative infection, haemorrhage or haematoma or seroma complicating a procedure, persistent postoperative fistula, perforation of bile duct and disruption of wound). (2) '30-day systemic complications' defined as any complications of other organs (including sepsis, infections from other organs, major cardiovascular events and selected adverse events).
results13 651 patients were included; 86.1% had LC, 13.9% OC. 2.0% experienced surgical-related complications (SRC), 2.1% systemic complications (SC). The OR of complications after LC versus OC was 0.60 (p<0.001) for SRC and 0.52 (p<0.001) for SC. In relation to SRC, the advantage of LC was consistent across age categories, severity of gallstones and previous upper abdominal surgery, whereas there was no advantage among people with emergency admission (OR=0.94, p=0.764). For SC, no significant advantage of LC was seen among very old people (OR=0.99, p=0.975) and among those with previous upper abdominal surgery (OR=0.86, p=0.905).
conclusionsThis large observational study confirms that LC is more effective than OC with respect to 30-day complications. Population-based linkage of administrative datasets can enlarge evidence of treatment benefits in clinical practice.
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