SynthesisInternational journal of colorectal disease2013
Use of FDG-PET or PET/CT to detect recurrent colorectal cancer in patients with elevated CEA: a systematic review and meta-analysis.
Synthesis in International journal of colorectal disease, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 105 citations in OpenAlex.
- Radiotherapy volume delineation based on MRI andAbdominal radiology (New York) · 2025Article
- Recurrent rectal cancer cured by transsacral prone longitudinal incision combined with bilateral gluteus maximus "kite" flap filling: a case report.Frontiers in oncology · 2025Article
- Diagnostic Performance of F-18 FDG PET/CT in the Detection of Recurrent Colorectal Cancer: Correlation with Biochemical Markers and Conventional Imaging Modalities.Journal of clinical medicine · 2024Article
- Clinical significance ofJournal of cancer research and clinical oncology · 2024Article
- Molecular profiling and patient selection for the multimodal approaches for patients with resectable colorectal liver metastases.Hepatobiliary surgery and nutrition · 2024Review
- Local Recurrences in Rectal Cancer: MRI vs. CT.Diagnostics (Basel, Switzerland) · 2023Review
- A Hybrid Algorithm of ML and XAI to Prevent Breast Cancer: A Strategy to Support Decision Making.Cancers · 2023Article
- The Clinical Significance of Incidental GIT Uptake on PET/CT: Radiologic, Endoscopic, and Pathologic Correlation.Diagnostics (Basel, Switzerland) · 2023Article
- Surveillance strategies following curative resection and non-operative approach of rectal cancer: How and how long? Review of current recommendations.World journal of gastrointestinal surgery · 2023Review
- Article
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- Variants and Pitfalls in PET/CT Imaging of Gastrointestinal Cancers.Seminars in nuclear medicine · 2021Review
- Implication of FDG-PET/CT without synchronous colonic lesion in patients with stenotic left-sided colorectal cancer.Scientific reports · 2021Article
- Role of 18F-FDG PET/CT in the Follow-up of Colorectal Cancer.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2020Article
- Metastatic rectal cancer to papillary thyroid carcinoma: a case report and review of literature.BMC gastroenterology · 2020Review
- Multidisciplinary management of liver metastases in patients with colorectal cancer: a consensus of SEOM, AEC, SEOR, SERVEI, and SEMNIM.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2020Article
- Clinical impact of PET/MR in treated colorectal cancer patients.European journal of nuclear medicine and molecular imaging · 2019Observational
- [Importance of FDG-PET/computed tomography in colorectal cancer].Der Radiologe · 2019Review
- Clinical Significance of Fluorine-18-fluorodeoxyglucose Positron Emission Tomography/computed Tomography in the Follow-up of Colorectal Cancer: Searching off Approaches Increasing Specificity for Detection of Recurrence.Radiology and oncology · 2017Article
- Present and future roles of FDG-PET/CT imaging in the management of gastrointestinal cancer: an update.Nagoya journal of medical science · 2017Review
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThe purpose of the present study was to conduct a systematic review and meta-analysis of the published literature to assess the diagnostic performance of FDG-PET or PET/CT in the detection of recurrent colorectal cancer (CRC) rising in patients with elevated CEA. MATERIALS AND
methodsThe authors conducted a systematic MEDLINE search of published articles. Two reviewers independently assessed the methodological quality of each study. We estimated pooled sensitivity and specificity and positive and negative likelihood ratios, and summary receiver-operating characteristic curves in the detection of recurrent CRC in patients with elevated CEA.
resultsEleven studies with a total of 510 patients met the inclusion criteria. One hundred and six patients (106/510 = 20.8%) had true-negative FDG-PET (PET/CT) results in detection of recurrent CRC when rising CEA. The pooled estimates of sensitivity and specificity and positive and negative likelihood ratios of FDG-PET in the detection of tumor recurrence in CRC patients with elevated CEA were 90.3% (95% CI, 85.5-94.0%), 80.0% (95% CI, 67.0-89.6%), 2.88 (95% CI, 1.37-6.07), and 0.12 (95% CI, 0.07-0.20), respectively. The pooled estimates of sensitivity and specificity and positive and negative likelihood ratios of FDG-PET/CT in the detection of tumor recurrence in CRC patients with elevated CEA were 94.1% (95% CI, 89.4-97.1%), 77.2% (95% CI, 66.4-85.9%), 4.70 (95% CI, 0.82-12.13), and 0.06 (95% CI, 0.03-0.13), respectively.
conclusionsWhole-body FDG-PET and PET/CT are valuable imaging tools for the assessment of patients with suspected CRC tumor recurrence based on the increase of CEA.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.