ArticleProceedings. Biological sciences2013
A family of diatom-like silicon transporters in the siliceous loricate choanoflagellates.
Article in Proceedings. Biological sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 55 citations in OpenAlex.
- Innovations in Silicon Transport Shaped the Rise of Biosilicification and Skeletal Evolution in Sponges.Molecular biology and evolution · 2026Article
- Article
- Characterization of the molecular mechanisms of silicon uptake in coccolithophores.Environmental microbiology · 2023Article
- Detection of horizontal gene transfer in the genome of the choanoflagellate Salpingoeca rosetta.Scientific reports · 2021Article
- Soluble silica stimulates osteogenic differentiation and gap junction communication in human dental follicle cells.Scientific reports · 2020Article
- Genome editing enables reverse genetics of multicellular development in the choanoflagellateeLife · 2020Article
- Growth and single cell kinetics of the loricate choanoflagellate Diaphanoeca grandis.Scientific reports · 2019Article
- Phytolith Formation in Plants: From Soil to Cell.Plants (Basel, Switzerland) · 2019Review
- A genomic survey of transposable elements in the choanoflagellateMobile DNA · 2019Article
- A family of silicon transporter structural genes in a pennate diatom Synedra ulna subsp. danica (Kütz.) Skabitsch.PloS one · 2018Article
- Identification of a mammalian silicon transporter.American journal of physiology. Cell physiology · 2017Article
- The Evolution of Silicon Transport in Eukaryotes.Molecular biology and evolution · 2016Article
- The evolution of silicon transporters in diatoms.Journal of phycology · 2016Article
- A model for the effects of germanium on silica biomineralization in choanoflagellates.Journal of the Royal Society, Interface · 2016Article
- Direct evidence of the molecular basis for biological silicon transport.Nature communications · 2016Article
- A role for diatom-like silicon transporters in calcifying coccolithophores.Nature communications · 2016Article
- Silaffins in Silica Biomineralization and Biomimetic Silica Precipitation.Marine drugs · 2015Review
- Silicon in vascular plants: uptake, transport and its influence on mineral stress under acidic conditions.Planta · 2015Review
- Article
- Bacterial influences on animal origins.Cold Spring Harbor perspectives in biology · 2014Review
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Authors and funding
7 authors at 5 institutions in 2 countries.
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Abstract
Biosilicification is widespread across the eukaryotes and requires concentration of silicon in intracellular vesicles. Knowledge of the molecular mechanisms underlying this process remains limited, with unrelated silicon-transporting proteins found in the eukaryotic clades previously studied. Here, we report the identification of silicon transporter (SIT)-type genes from the siliceous loricate choanoflagellates Stephanoeca diplocostata and Diaphanoeca grandis. Until now, the SIT gene family has been identified only in diatoms and other siliceous stramenopiles, which are distantly related to choanoflagellates among the eukaryotes. This is the first evidence of similarity between SITs from different eukaryotic supergroups. Phylogenetic analysis indicates that choanoflagellate and stramenopile SITs form distinct monophyletic groups. The absence of putative SIT genes in any other eukaryotic groups, including non-siliceous choanoflagellates, leads us to propose that SIT genes underwent a lateral gene transfer event between stramenopiles and loricate choanoflagellates. We suggest that the incorporation of a foreign SIT gene into the stramenopile or choanoflagellate genome resulted in a major metabolic change: the acquisition of biomineralized silica structures. This hypothesis implies that biosilicification has evolved multiple times independently in the eukaryotes, and paves the way for a better understanding of the biochemical basis of silicon transport through identification of conserved sequence motifs.
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