ArticleNature2013
Abundant SAR11 viruses in the ocean.
Article in Nature, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 197 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
197 citing papers in PubMed.
- The planktonic microbiome of the Great Barrier Reef.Nature · 2026Article
- From hijackers to architects: the role of prophages in bacterial genome evolution.Journal of bacteriology · 2026Review
- DNA virus-host patterns in lake and marine environments over the last glacial cycle.The ISME journal · 2026Article
- Dispersal pathways and infection strategies within the Global Halophilic Virome.ISME communications · 2026Article
- Heterotrophic Prokaryote Host-Virus Dynamics During Spring in the Northeast Atlantic Ocean.Microorganisms · 2025Article
- Cryo-EM resolves the structure of the archaeal dsDNA virus HFTV1 from head to tail.Science advances · 2025Article
- Marine Autographiviridae phages exhibit high genetic diversity and global-scale biogeographic patterns.Communications biology · 2025Article
- Isolation, complete characterization and phylogeography of the first bacteriophage againstMicrobial genomics · 2025Article
- Microbial community structure is affected by phage-resistance associated increases in host density.FEMS microbiology ecology · 2025Article
- Targeted genomic analysis of a predominant uncultured marine pelagiphage-host model via microfluidics and semipermeable capsule technology.ISME communications · 2025Article
- Comparative transcriptomes reveal differential effects on host metabolism reprogramming in two different pelagiphage-SAR11 infection systems.ISME communications · 2025Article
- Non-coding RNAs as key regulators of epithelial-mesenchymal transition in breast cancer.Frontiers in cell and developmental biology · 2025Review
- A novel virus potentially evolved from the N4-like viruses represents a unique viral family:Applied and environmental microbiology · 2024Article
- Article
- Diversity and distribution of a prevalent Microviridae group across the global oceans.Communications biology · 2024Article
- Novel phage infecting themSphere · 2024Article
- Long-read powered viral metagenomics in the oligotrophic Sargasso Sea.Nature communications · 2024Article
- Globally occurring pelagiphage infections create ribosome-deprived cells.Nature communications · 2024Article
- Nanopore and Illumina sequencing reveal different viral populations from human gut samples.Microbial genomics · 2024Article
- Genome sequences of the firstMicrobial genomics · 2024Article
137 more citing papers are in PubMed but not listed here.
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Authors and funding
10 authors.
Funding
Abstract
Several reports proposed that the extraordinary dominance of the SAR11 bacterial clade in ocean ecosystems could be a consequence of unusual mechanisms of resistance to bacteriophage infection, including 'cryptic escape' through reduced cell size and/or K-strategist defence specialism. Alternatively, the evolution of high surface-to-volume ratios coupled with minimal genomes containing high-affinity transporters enables unusually efficient metabolism for oxidizing dissolved organic matter in the world's oceans that could support vast population sizes despite phage susceptibility. These ideas are important for understanding plankton ecology because they emphasize the potentially important role of top-down mechanisms in predation, thus determining the size of SAR11 populations and their concomitant role in biogeochemical cycling. Here we report the isolation of diverse SAR11 viruses belonging to two virus families in culture, for which we propose the name 'pelagiphage', after their host. Notably, the pelagiphage genomes were highly represented in marine viral metagenomes, demonstrating their importance in nature. One of the new phages, HTVC010P, represents a new podovirus subfamily more abundant than any seen previously, in all data sets tested, and may represent one of the most abundant virus subfamilies in the biosphere. This discovery disproves the theory that SAR11 cells are immune to viral predation and is consistent with the interpretation that the success of this highly abundant microbial clade is the result of successfully evolved adaptation to resource competition.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.