Trial reportHuman molecular genetics2013
Absolute pitch exhibits phenotypic and genetic overlap with synesthesia.
Trial report in Human molecular genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.
- Conceptual coherence but methodological mayhem: A systematic review of absolute pitch phenotyping.Behavior research methods · 2025Pooled it
- Brain structural morphometry in non-musicians with superior pitch identification ability.Scientific reports · 2026Article
- One- or two-step? New insights into two-step hypothesis and rainbow-like theory for pitch class-color synesthesia.Frontiers in psychology · 2024Article
- Auditory temporal resolution and backward masking in musicians with absolute pitch.Frontiers in neuroscience · 2023Article
- Use of explicit priming to phenotype absolute pitch ability.PloS one · 2022Article
- Review
- Strategies Used by Musicians to Identify Notes' Pitch: Cognitive Bricks and Mental Representations.Frontiers in psychology · 2020Article
- Investigating genetic links between grapheme-colour synaesthesia and neuropsychiatric traits.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Article
- Stochastic resonance model of synaesthesia.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Review
- A Tendency Towards Details? Inconsistent Results on Auditory and Visual Local-To-Global Processing in Absolute Pitch Musicians.Frontiers in psychology · 2019Article
- Autistic traits, resting-state connectivity, and absolute pitch in professional musicians: shared and distinct neural features.Molecular autism · 2019Article
- Rare variants in axonogenesis genes connect three families with sound-color synesthesia.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Convergent evidence for the molecular basis of musical traits.Scientific reports · 2016Review
- Synesthesia strengthens sound-symbolic cross-modal correspondences.The European journal of neuroscience · 2016Article
- Detecting signatures of positive selection associated with musical aptitude in the human genome.Scientific reports · 2016Article
- Defining the biological bases of individual differences in musicality.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2015Review
- The music of the genes.Investigative genetics · 2014Article
- The genetic basis of music ability.Frontiers in psychology · 2014Review
- Veridical mapping in savant abilities, absolute pitch, and synesthesia: an autism case study.Frontiers in psychology · 2014Article
- Is synaesthesia more common in autism?Molecular autism · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 4 countries.
Funding
Abstract
Absolute pitch (AP) and synesthesia are two uncommon cognitive traits that reflect increased neuronal connectivity and have been anecdotally reported to occur together in an individual. Here we systematically evaluate the occurrence of synesthesia in a population of 768 subjects with documented AP. Out of these 768 subjects, 151 (20.1%) reported synesthesia, most commonly with color. These self-reports of synesthesia were validated in a subset of 21 study subjects, using an established methodology. We further carried out combined linkage analysis of 53 multiplex families with AP and 36 multiplex families with synesthesia. We observed a peak NPL LOD = 4.68 on chromosome 6q, as well as evidence of linkage on chromosome 2, using a dominant model. These data establish the close phenotypic and genetic relationship between AP and synesthesia. The chromosome 6 linkage region contains 73 genes; several leading candidate genes involved in neurodevelopment were investigated by exon resequencing. However, further studies will be required to definitively establish the identity of the causative gene(s) in the region.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.