Evidence map›Paper›PMID 23406786›Full record

ArticleArtificial DNA, PNA & XNA

Bending of short DNA helices.

Alexander Vologodskii, Quan Du, Maxim D Frank-Kamenetskii

Abstract readComment
In one paragraph

Article in Artificial DNA, PNA & XNA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Role of microscopic flexibility in tightly curved DNA.The journal of physical chemistry. B · 2014
    Article
  7. Studying DNA looping by single-molecule FRET.Journal of visualized experiments : JoVE · 2014
    Article
  8. Probing the elastic limit of DNA bending.Nucleic acids research · 2014
    Article
  9. Strong bending of the DNA double helix.Nucleic acids research · 2013
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Alexander VologodskiiDeparment of Chemistry, New York University, New York, NY, USA. alex.vologodskii@nyu.edu
Quan Du
Maxim D Frank-Kamenetskii

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In their recent Science paper, Vafabakhsh and Ha claim that DNA duplexes at the range of 100 bp experience anomalous flexibility, much greater than the flexibility of large DNA molecules. ( 1) However, careful reevaluation of their data leads to the conclusion that the presented data do not warrant the authors' claim.

Indexed as

Nucleic Acid ConformationDNA, CircularFluorescence Resonance Energy TransferDNA, CircularDNA bending flexibilityDNA extreme bendabilityDNA minicirclesDNA sticky endssingle-molecule data

Identifiers

PMID23406786
PMCPMC3654724

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.