SynthesisPloS one2013
Obesity and the microvasculature: a systematic review and meta-analysis.
Synthesis in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 2 syntheses or guidelines pooled it, 134 citations in OpenAlex.
- Effect of Bariatric Surgery on Improvement of Retinal Microvasculature in Patients With Obesity: A Systematic Review and Meta-Analysis.Clinical obesity · 2026Pooled it
- Pooled it
- Randomized 20-year infancy-onset dietary intervention, life-long cardiovascular risk factors and retinal microvasculature.European heart journal · 2024Trial
- Advancing Retinal Vessel Analysis: Reproducibility of Myogenic Constriction and Assessment of Regulatory Capacity.Translational vision science & technology · 2026Article
- Associations between anthropometric and body composition indices with subclinical arterial damage in chronic inflammatory diseases.International journal of obesity (2005) · 2026Article
- Body mass index, not local adiposity, best predicts surgical site infection following surgical fixation of distal femur fractures.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026Article
- Selected Aspects of Optical Coherence Tomography and Adaptive Optics in Patients with Increased Body Mass Index.Biomedicines · 2026Article
- Beyond the Scale: Obesity as a Structural Driver of Refractory Hypertension.Arquivos brasileiros de cardiologia · 2026Article
- Relationship Between Retinal Vascular Measurements and Anthropometric Indices in Patients Diagnosed with Persistent COVID-19.Journal of clinical medicine · 2025Article
- Meta-analysis of the effects of physical activity on ocular biometrics in children and adolescents.Frontiers in public health · 2025Article
- Article
- Article
- Obesity, body fat distribution and eye diseases.Eating and weight disorders : EWD · 2024Review
- Contribution of systemic factors on macular vessel density: a sex-specific population-based study.Japanese journal of ophthalmology · 2024Article
- Free-moving-state microscopic imaging of cerebral oxygenation and hemodynamics with a photoacoustic fiberscope.Light, science & applications · 2024Article
- Adipocentric origin of the common cardiometabolic complications of obesity in the young up to the very old: pathophysiology and new therapeutic opportunities.Frontiers in medicine · 2024Review
- How Does Weight Loss After Bariatric Surgery Impact the Ocular Parameters? A Review.Obesity surgery · 2023Review
- Sleeve gastrectomy improved microvascular phenotypes from obesity cohort, detected with optical coherence tomography angiography.Journal of diabetes · 2023Article
- Cardiorespiratory fitness and development of childhood cardiovascular risk: The EXAMIN YOUTH follow-up study.Frontiers in physiology · 2023Article
- Lipoprotein Subclasses Independently Contribute to Subclinical Variance of Microvascular and Macrovascular Health.Molecules (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 12 institutions in 9 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOverweight and obesity are thought to significantly influence a person's risk of cardiovascular disease, possibly via its effect on the microvasculature. Retinal vascular caliber is a surrogate marker of microvascular disease and a predictor of cardiovascular events. The aim of this systematic review and meta-analysis was to determine the association between body mass index (BMI) and retinal vascular caliber. METHODS AND
findingsRelevant studies were identified by searches of the MEDLINE and EMBASE databases from 1966 to August 2011. Standardized forms were used for data extraction. Among over 44,000 individuals, obese subjects had narrower arteriolar and wider venular calibers when compared with normal weight subjects, independent of conventional cardiovascular risk factors. In adults, a 1 kg/m(2) increase in BMI was associated with a difference of 0.07 μm [95% CI: -0.08; -0.06] in arteriolar caliber and 0.22 μm [95% CI: 0.21; 0.23] in venular caliber. Similar results were found for children.
conclusionsHigher BMI is associated with narrower retinal arteriolar and wider venular calibers. Further prospective studies are needed to examine whether a causative relationship between BMI and retinal microcirculation exists.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.