ArticlePlant physiology2013
The Rab GTPase RabG3b positively regulates autophagy and immunity-associated hypersensitive cell death in Arabidopsis.
Article in Plant physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
74 citing papers in PubMed, 127 citations in OpenAlex.
- Ethylene as the Molecular Coordinator of the Plant Growth-Defense Trade-Off Under Biotic and Abiotic Stresses.International journal of molecular sciences · 2026Review
- Autophagy-Mediated Adaptation: Revealing the Role of Autophagy in Plant Responses to Abiotic Stress.Genes · 2025Review
- Late blight pathogen targets host Rab-G3 GTPases with an atypical GTPase-activating protein.Journal of integrative plant biology · 2025Article
- The N-degron pathway governs autophagy to promote thermotolerance in Arabidopsis.Nature communications · 2025Article
- Genome-Wide Characterization and Expression Analysis of the Cysteine-Rich Polycomb-like Protein Gene Family in Response to Hormone Signaling in Apple (International journal of molecular sciences · 2025Article
- Beyond glycolysis: multifunctional roles of glyceraldehyde-3-phosphate dehydrogenases in plants.Horticulture research · 2025Article
- The TRAPPC8/TRS85 subunit of the Arabidopsis TRAPPIII tethering complex regulates endoplasmic reticulum function and autophagy.Plant physiology · 2025Article
- Autophagy and Bacterial infections.Autophagy reports · 2025Review
- Physiological and differential protein expression analyses of the calcium stress response in theHeliyon · 2024Article
- MAPK20-mediated ATG6 phosphorylation is critical for pollen development inHorticulture research · 2024Article
- Structural diversification of fungal cell wall in response to the stress signaling and remodeling during fungal pathogenesis.Physiology and molecular biology of plants : an international journal of functional plant biology · 2024Review
- Molecular Machinery of Lipid Droplet Degradation and Turnover in Plants.International journal of molecular sciences · 2023Review
- Studying plant autophagy: challenges and recommended methodologies.Advanced biotechnology · 2023Review
- Transcriptional and post-translational regulation of plant autophagy.Journal of experimental botany · 2023Review
- NET4 and RabG3 link actin to the tonoplast and facilitate cytoskeletal remodelling during stomatal immunity.Nature communications · 2023Article
- Emerging role of small GTPases and their interactome in plants to combat abiotic and biotic stress.Protoplasma · 2023Review
- Silencing of the calcium-dependent protein kinase TaCDPK27 improves wheat resistance to powdery mildew.BMC plant biology · 2023Article
- Pathogen-induced autophagy regulates monolignol transport and lignin formation in plant immunity.Autophagy · 2023Article
- RAB7 GTPases as coordinators of plant endomembrane traffic.Frontiers in plant science · 2023Review
- Membrane contact sites and cytoskeleton-membrane interactions in autophagy.FEBS letters · 2022Review
14 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A central component of the plant defense response to pathogens is the hypersensitive response (HR), a form of programmed cell death (PCD). Rapid and localized induction of HR PCD ensures that pathogen invasion is prevented. Autophagy has been implicated in the regulation of HR cell death, but the functional relationship between autophagy and HR PCD and the regulation of these processes during the plant immune response remain controversial. Here, we show that a small GTP-binding protein, RabG3b, plays a positive role in autophagy and promotes HR cell death in response to avirulent bacterial pathogens in Arabidopsis (Arabidopsis thaliana). Transgenic plants overexpressing a constitutively active RabG3b (RabG3bCA) displayed accelerated, unrestricted HR PCD within 1 d of infection, in contrast to the autophagy-defective atg5-1 mutant, which gradually developed chlorotic cell death through uninfected sites over several days. Microscopic analyses showed the accumulation of autophagic structures during HR cell death in RabG3bCA cells. Our results suggest that RabG3b contributes to HR cell death via the activation of autophagy, which plays a positive role in plant immunity-triggered HR PCD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.