ArticleThe oncologist2013
Factors associated with fatigue after surgery in women with early-stage invasive breast cancer.
Article in The oncologist, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03217201 (Systematic Light Exposure to Treat Cancer-Related Fatigue in Breast Cancer Patients), which is not on this map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Systematic Light Exposure to Treat Cancer-Related Fatigue in Breast Cancer Patients
Who cites it
12 citing papers in PubMed, 26 citations in OpenAlex.
- Predictors of fatigue improvement in multimodal, multimodal-aerobic and aerobic exercise intervention studies in breast cancer survivors with cancer-related fatigue.Scientific reports · 2025Trial
- Phase 2 Open-Label Trial Investigating Percutaneous Laser Ablation for Treatment of Early-Stage Breast Cancer: MRI, Pathology, and Outcome Correlations.Annals of surgical oncology · 2018Trial
- Pre-operative and early postoperative health-related quality of life of breast cancer woman: a Lebanese prospective study.BMC women's health · 2023Article
- Fatigue and resting-state functional brain networks in breast cancer patients treated with chemotherapy.Breast cancer research and treatment · 2021Article
- Accelerated aging in breast cancer survivors and its association with mortality and cancer recurrence.Breast cancer research and treatment · 2020Article
- Keystone Perforator Island Flap for Postmastectomy Defect Resurfacing in Late-stage Breast Cancer Patients.Plastic and reconstructive surgery. Global open · 2019Article
- Fatigue and Functional Ability in Patients Undergoing Upfront Surgical Treatment for Solid Malignancies.Indian journal of surgical oncology · 2019Article
- Testing a biobehavioral model of fatigue before adjuvant therapy in women with breast cancer.Cancer · 2019Article
- Polymorphisms in Cytokine Genes Are Associated With Higher Levels of Fatigue and Lower Levels of Energy in Women After Breast Cancer Surgery.Journal of pain and symptom management · 2016Article
- Article
- Toward unraveling the correlates of fatigue in glioma.Neuro-oncology advancesArticle
- Cluster Analysis of Symptoms of Bangladeshi Women with Breast Cancer.Indian journal of palliative careArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeFatigue is one of the most frequent symptoms in patients with cancer. However, the precise determinants of fatigue are still unknown. This study was conducted to investigate factors correlated with cancer-related fatigue before surgery and just before subsequent adjuvant therapy.
methodsPatients completed the Multidimensional Fatigue Inventory (MFI-20), the European Organization for Research and Treatment of Cancer 30-item quality-of-life questionnaire before and after surgery, the Trait Anxiety Inventory and the Life Orientation Test before surgery, and the State Anxiety Inventory before the start of adjuvant therapy. Multiple regression analysis of determinants of change in MFI-20 total score after surgery was conducted.
resultsA series of 466 eligible patients with stage I-III breast cancer with planned surgery were recruited. An increase in MFI-20 total score after surgery was significantly correlated with higher preoperative fatigue and lower role functioning before surgery; a decrease in role functioning, physical functioning, and cognitive functioning after surgery; an increase in insomnia after surgery; and a higher state anxiety after surgery. Disease stage, lymph node metastases, surgical procedure, and demographic characteristics (e.g., age, marital status, having children, educational level) were not correlated with fatigue in multivariate analysis.
conclusionThese results suggest that worsening fatigue after surgery for breast cancer is associated with a decrease in physical functioning and an increase in psychological distress rather than with the cancer characteristics. Therefore, screening measures should be implemented at the time of diagnosis-before starting treatment-to identify psychologically vulnerable patients and to offer them professional support.
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