ReviewCurrent opinion in virology2013
Animal models for highly pathogenic emerging viruses.
Review in Current opinion in virology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- SARS-CoV-2 immunity in animal models.Cellular & molecular immunology · 2024Review
- Praemonitus praemunitus: can we forecast and prepare for future viral disease outbreaks?FEMS microbiology reviews · 2023Review
- Self-amplifying RNA vaccine protects mice against lethal Ebola virus infection.Molecular therapy : the journal of the American Society of Gene Therapy · 2023Article
- An Updated Review of SARS-CoV-2 Vaccines and the Importance of Effective Vaccination Programs in Pandemic Times.Vaccines · 2021Review
- A hSCARB2-transgenic mouse model for Coxsackievirus A16 pathogenesis.Virology journal · 2021Article
- Non-human Primate Models to Investigate Mechanisms of Infection-Associated Fetal and Pediatric Injury, Teratogenesis and Stillbirth.Frontiers in genetics · 2021Review
- Human Organs-on-Chips for Virology.Trends in microbiology · 2020Review
- Broad and Differential Animal Angiotensin-Converting Enzyme 2 Receptor Usage by SARS-CoV-2.Journal of virology · 2020Article
- Evidence for SARS-CoV-2 Infection of Animal Hosts.Pathogens (Basel, Switzerland) · 2020Review
- Mus musculus Papillomavirus 1: a New Frontier in Animal Models of Papillomavirus Pathogenesis.Journal of virology · 2020Review
- Precision mouse models with expanded tropism for human pathogens.Nature biotechnology · 2019Article
- Zika Virus Infection in Syrian Golden Hamsters and Strain 13 Guinea Pigs.The American journal of tropical medicine and hygiene · 2018Article
- Type I interferon receptor knockout mice as models for infection of highly pathogenic viruses with outbreak potential.Zoological research · 2018Article
- Article
- Searching for animal models and potential target species for emerging pathogens: Experience gained from Middle East respiratory syndrome (MERS) coronavirus.One health (Amsterdam, Netherlands) · 2017Review
- Evaluation of Ebola Virus Countermeasures in Guinea Pigs.Methods in molecular biology (Clifton, N.J.) · 2017Article
- Limited susceptibility of rhesus macaques to a cowpox virus isolated from a lethal outbreak among New World monkeys.Primate biology · 2017Article
- Gain-of-Function Research and the Relevance to Clinical Practice.The Journal of infectious diseases · 2016Review
- Article
- Development of Small-Molecule Antivirals for Ebola.Medicinal research reviews · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Exotic and emerging viral pathogens associated with high morbidity and mortality in humans are being identified annually with recent examples including Lujo virus in southern Africa, Severe Fever with Thrombocytopenia Syndrome virus in China and a SARS-like coronavirus in the Middle East. The sporadic nature of these infections hampers our understanding of these diseases and limits the opportunities to design appropriate medical countermeasures against them. Because of this, animal models are utilized to gain insight into the pathogenesis of disease with the overall goal of identifying potential targets for intervention and evaluating specific therapeutics and vaccines. For these reasons it is imperative that animal models of disease recapitulate the human condition as closely as possible in order to provide the best predictive data with respect to the potential efficacy in humans. In this article we review the current status of disease models for highly pathogenic and emerging viral pathogens.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.