Evidence map›Paper›PMID 23402960›Full record

ArticleJournal of biomedical informatics2013

The Analytic Information Warehouse (AIW): a platform for analytics using electronic health record data.

Andrew R Post, Tahsin Kurc, Sharath Cholleti, Jingjing Gao, Xia Lin, William Bornstein, Dedra Cantrell, David Levine, Sam Hohmann, Joel H Saltz

Abstract read
In one paragraph

Article in Journal of biomedical informatics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Clinical Data Warehousing: A Scoping Review.Journal of the Society for Clinical Data Management · 2024
    Article
  2. Article
  3. Review
  4. Deep Learning on Electronic Health Records to Improve Disease Coding Accuracy.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2019
    Article
  5. A Method for EHR Phenotype Management in an i2b2 Data Warehouse.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2019
    Article
  6. Review
  7. Article
  8. Urinary Angiogenin Reflects the Magnitude of Kidney Injury at the Infrahistologic Level.Journal of the American Society of Nephrology : JASN · 2017
    Article
  9. Article
  10. Article
  11. Metadata-driven Clinical Data Loading into i2b2 for Clinical and Translational Science Institutes.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2016
    Article
  12. R-U policy frontiers for health data de-identification.Journal of the American Medical Informatics Association : JAMIA · 2015
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Temporal abstraction-based clinical phenotyping with Eureka!AMIA ... Annual Symposium proceedings. AMIA Symposium · 2013
    Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Andrew R PostDepartment of Biomedical Informatics, Emory University, 36 Eagle Row, Atlanta, GA 30322, USA. arpost@emory.edu
Tahsin Kurc
Sharath Cholleti
Jingjing Gao
Xia Lin
William Bornstein
Dedra Cantrell
David Levine
Sam Hohmann
Joel H Saltz

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025008 · NCRR · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2007 to 2011
$29.0M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
Research Desogn and Biostatistics CoreU54MD007588 · NIMHD · MOREHOUSE SCHOOL OF MEDICINE · PI MAYBERRY, ROBERT M · 2012 to 2018
$24.8M
X LINKED NYSTAGMUS SYNDROME WITH FEATURES OF ALBINISMM01RR000039 · NCRR · EMORY UNIVERSITY · PI VACCARINO, VIOLA · 1985 to 2007
$21.3M
The CardioVascular Research GridR24HL085343 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI WINSLOW, RAIMOND LESTER · 2007 to 2015
$19.4M
WARCEFU54RR026137 · NCRR · MOREHOUSE SCHOOL OF MEDICINE · PI CONERLY HOLLIDAY, RHONDA C · 2009 to 2011
$14.6M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalKL2TR000455 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$2.9M
Atlanta Clinical and Translational Science Institute (KL2)KL2RR025009 · NCRR · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2007 to 2011
$2.9M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalTL1TR000456 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$1.2M
Atlanta Clinical and Translational Science Institute (TL1)TL1RR025010 · NCRR · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2007 to 2011
$1.1M
NCATS NIH HHS KL2 TR000455NCATS NIH HHS TL1 TR000456NCATS NIH HHS UL1 TR000454NCRR NIH HHS KL2 RR025009NCRR NIH HHS M01 RR000039NCRR NIH HHS TL1 RR025010NCRR NIH HHS U54 RR026137NCRR NIH HHS UL1 RR025008NHLBI NIH HHS R24 HL085343NIMHD NIH HHS U54 MD007588
6 · The paper itself

Abstract

objectiveTo create an analytics platform for specifying and detecting clinical phenotypes and other derived variables in electronic health record (EHR) data for quality improvement investigations. MATERIALS AND

methodsWe have developed an architecture for an Analytic Information Warehouse (AIW). It supports transforming data represented in different physical schemas into a common data model, specifying derived variables in terms of the common model to enable their reuse, computing derived variables while enforcing invariants and ensuring correctness and consistency of data transformations, long-term curation of derived data, and export of derived data into standard analysis tools. It includes software that implements these features and a computing environment that enables secure high-performance access to and processing of large datasets extracted from EHRs.

resultsWe have implemented and deployed the architecture in production locally. The software is available as open source. We have used it as part of hospital operations in a project to reduce rates of hospital readmission within 30days. The project examined the association of over 100 derived variables representing disease and co-morbidity phenotypes with readmissions in 5years of data from our institution's clinical data warehouse and the UHC Clinical Database (CDB). The CDB contains administrative data from over 200 hospitals that are in academic medical centers or affiliated with such centers. DISCUSSION AND

conclusionA widely available platform for managing and detecting phenotypes in EHR data could accelerate the use of such data in quality improvement and comparative effectiveness studies.

Indexed as

Electronic Health RecordsSoftwareAlgorithmsDatabase Management SystemsPatient Readmission

Identifiers

PMID23402960
PMCPMC3660520

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.