ReviewJournal of cystic fibrosis : official journal of the European Cystic Fibrosis Society2013
Molecular detection of CF lung pathogens: current status and future potential.
Review in Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Bacterial Culture Underestimates Lung Pathogen Detection and Infection Status in Cystic Fibrosis.Microbiology spectrum · 2022Article
- Genomic diversity and antimicrobial resistance ofMicrobial genomics · 2022Article
- Lung function and microbiota diversity in cystic fibrosis.Microbiome · 2020Article
- Cooperativity between Stenotrophomonas maltophilia and Pseudomonas aeruginosa during Polymicrobial Airway Infections.Infection and immunity · 2020Article
- Detection of viable but non-culturable Pseudomonas aeruginosa in cystic fibrosis by qPCR: a validation study.BMC infectious diseases · 2018Article
- Article
- Respiratory microbiota resistance and resilience to pulmonary exacerbation and subsequent antimicrobial intervention.The ISME journal · 2016Article
- Article
- A French multicentric study and review of pulmonary Nocardia spp. in cystic fibrosis patients.Medical microbiology and immunology · 2015Article
- Implications of multiple freeze-thawing on respiratory samples for culture-independent analyses.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2015Article
- Pulmonary nocardiosis in an immunocompetent patient with cystic fibrosis.Case reports in pulmonology · 2015Article
- Antibiotic management of lung infections in cystic fibrosis. I. The microbiome, methicillin-resistant Staphylococcus aureus, gram-negative bacteria, and multiple infections.Annals of the American Thoracic Society · 2014Review
- Polybacterial human disease: the ills of social networking.Trends in microbiology · 2014Review
- Time between collection and storage significantly influences bacterial sequence composition in sputum samples from cystic fibrosis respiratory infections.Journal of clinical microbiology · 2014Article
- Universal digital high-resolution melt: a novel approach to broad-based profiling of heterogeneous biological samples.Nucleic acids research · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Molecular diagnostic tests, based on the detection and identification of nucleic acids in human biological samples, are increasingly employed in the diagnosis of infectious diseases and may be of future benefit to CF microbiology services. Our growing understanding of the complex polymicrobial nature of CF airway infection has highlighted current and likely future shortcomings in standard diagnostic practices. Failure to detect fastidious or slow growing microbes and misidentification of newly emerging pathogens could potentially be addressed using culture-independent molecular technologies with high target specificity. This review considers existing molecular diagnostic tests in the context of the key requirements for an envisaged CF microbiology focussed assay. The issues of assay speed, throughput, detection of multiple pathogens, data interpretation and antimicrobial susceptibility testing are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.