ReviewJournal of cellular and molecular medicine2013
Bioluminescence imaging: a shining future for cardiac regeneration.
Review in Journal of cellular and molecular medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- An emphatic study on the luciferin-luciferase bioluminescence system of Benthosema pterotum.Fish physiology and biochemistry · 2023Article
- Calcium and Heart Failure: How Did We Get Here and Where Are We Going?International journal of molecular sciences · 2021Review
- Mesenchymal Stem Cell Therapy for Ischemic Tissues.Stem cells international · 2018Review
- Optical spectroscopic imaging for cell therapy and tissue engineering.Applied spectroscopy reviews · 2018Article
- Multimodal Hydrogel-Based Platform To Deliver and Monitor Cardiac Progenitor/Stem Cell Engraftment.ACS central science · 2017Article
- New Bioengineering Breakthroughs and Enabling Tools in Regenerative Medicine.Current stem cell reports · 2017Review
- In Vivo Tracking of Cell Therapies for Cardiac Diseases with Nuclear Medicine.Stem cells international · 2016Review
- In vivo bioluminescence imaging of hyperglycemia exacerbating stem cells on choroidal neovascularization in mice.International journal of ophthalmology · 2016Article
- Postinfarction Functional Recovery Driven by a Three-Dimensional Engineered Fibrin Patch Composed of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells.Stem cells translational medicine · 2015Article
- The role and potential of umbilical cord blood in an era of new therapies: a review.Stem cell research & therapy · 2015Review
- Clinical imaging in regenerative medicine.Nature biotechnology · 2014Review
- Toward a systems-level view of dynamic phosphorylation networks.Frontiers in genetics · 2014Review
- The angiogenic properties of mesenchymal stem/stromal cells and their therapeutic potential.British medical bulletin · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Advances in bioanalytical techniques have become crucial for both basic research and medical practice. One example, bioluminescence imaging (BLI), is based on the application of natural reactants with light-emitting capabilities (photoproteins and luciferases) isolated from a widespread group of organisms. The main challenges in cardiac regeneration remain unresolved, but a vast number of studies have harnessed BLI with the discovery of aequorin and green fluorescent proteins. First described in the luminous hydromedusan Aequorea victoria in the early 1960s, bioluminescent proteins have greatly contributed to the design and initiation of ongoing cell-based clinical trials on cardiovascular diseases. In conjunction with advances in reporter gene technology, BLI provides valuable information about the location and functional status of regenerative cells implanted into numerous animal models of disease. The purpose of this review was to present the great potential of BLI, among other existing imaging modalities, to refine effectiveness and underlying mechanisms of cardiac cell therapy. We recount the first discovery of natural primary compounds with light-emitting capabilities, and follow their applications to bioanalysis. We also illustrate insights and perspectives on BLI to illuminate current efforts in cardiac regeneration, where the future is bright.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.