ReviewAdvances in experimental medicine and biology2013
Complement-targeted therapeutics in periodontitis.
Review in Advances in experimental medicine and biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 19 citations in OpenAlex.
- Periodontitis Primes the Oral Microenvironment for PS-Dependent Non-Canonical Entry Pathways Linked to SARS-CoV-2 Susceptibility.Research square · 2026Article
- The Oral-Gut-Brain Axis: The Influence of Microbes as a Link of Periodontitis With Ischemic Stroke.CNS neuroscience & therapeutics · 2024Review
- Molecular systems architecture of host-microbiome interactions in periodontitis.JADA foundational science · 2023Review
- Coaxial TP/APR electrospun nanofibers for programmed controlling inflammation and promoting bone regeneration in periodontitis-related alveolar bone defect models.Materials today. Bio · 2022Article
- Four-Octyl itaconate ameliorates periodontal destruction via Nrf2-dependent antioxidant system.International journal of oral science · 2022Article
- Applications of tetrahedral DNA nanostructures in wound repair and tissue regeneration.Burns & trauma · 2022Review
- The protective effect of tetrahedral framework nucleic acids on periodontium under inflammatory conditions.Bioactive materials · 2021Article
- Circadian Clock and Complement Immune System-Complementary Control of Physiology and Pathology?Frontiers in cellular and infection microbiology · 2020Review
- Role of the Complement System in the Response to Orthopedic Biomaterials.International journal of molecular sciences · 2018Review
- Periostin promotes migration and osteogenic differentiation of human periodontal ligament mesenchymal stem cells via the Jun amino-terminal kinases (JNK) pathway under inflammatory conditions.Cell proliferation · 2017Article
- Manipulation of Neutrophils byFrontiers in cellular and infection microbiology · 2017Review
- A Metalloproteinase Mirolysin of Tannerella forsythia Inhibits All Pathways of the Complement System.Journal of immunology (Baltimore, Md. : 1950) · 2015Article
- Compstatin: a C3-targeted complement inhibitor reaching its prime for bedside intervention.European journal of clinical investigation · 2015Review
- Complement Involvement in Periodontitis: Molecular Mechanisms and Rational Therapeutic Approaches.Advances in experimental medicine and biology · 2015Review
- Mechanisms of Bone Resorption in Periodontitis.Journal of immunology research · 2015Review
- Genetic and intervention studies implicating complement C3 as a major target for the treatment of periodontitis.Journal of immunology (Baltimore, Md. : 1950) · 2014Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Periodontitis is a prevalent oral chronic inflammatory disease which, in severe forms, may exert a major impact on systemic health. Clinical and histological observations, as well as experimental animal studies, suggest involvement of the complement system in periodontitis. However, the precise roles of the various complement components and pathways in periodontitis have only recently started to be elucidated. In this chapter, we review recent progress in the field and discuss the potential of complement-targeted therapeutics in the treatment of periodontitis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.