Trial reportMediators of inflammation2013
Time course of muscle damage and inflammatory responses to resistance training with eccentric overload in trained individuals.
Trial report in Mediators of inflammation, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 19 citations in OpenAlex.
- Effects of Immediate and Delayed Repeated Cold Exposure After Physical Exertion: A Randomized Controlled Trial.International journal of environmental research and public health · 2026Trial
- Acute metabolic, hormonal, and psychological responses to strength training with superimposed EMS at the beginning and the end of a 6 week training period.Journal of musculoskeletal & neuronal interactions · 2015Trial
- Systemic Degree of Perturbation of Plasma Markers Reveals Cumulative Biological Stress Across the Competitive Season in Professional Soccer Players.Sports medicine (Auckland, N.Z.) · 2026Article
- Impact of Weekly Eccentric Overload Training on Locomotor and Mechanical Performance in Youth Soccer Players.Journal of sports science & medicine · 2025Article
- Comparing the Effect of Isoinertial Flywheel Training and Traditional Resistance Training on Maximal Strength and Muscle Power in Healthy People: A Systematic Review and Meta-Analysis.Life (Basel, Switzerland) · 2024Review
- Effect of a strength or hypertrophy training protocol, each performed using two different modes of resistance, on biomechanical, biochemical and anthropometric parameters.Biology of sport · 2020Article
- Time-course responses of circulating microRNAs to three resistance training protocols in healthy young men.Scientific reports · 2017Article
- Profiling of exercise-induced transcripts in the peripheral blood cells of Thoroughbred horses.Journal of equine science · 2016Article
- Muscle damage responses and adaptations to eccentric-overload resistance exercise in men and women.European journal of applied physiology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this study was to observe the time course of muscle damage and inflammatory responses following an eccentric overload resistance-training (EO) program. 3 females (23.8 ± 2.6 years; 70.9 ± 12.7 kg; 1.6 ± 0.08 m) and 5 males (23.8 ± 2.6 years; 75.1 ± 11.2 kg; 1.8 ± 0.1 m) underwent thirteen training sessions (4 × 8-10 eccentric-only repetitions-80% of eccentric 1RM, one-minute rest, 2x week(-1), during 7 weeks, for three exercises). Blood samples were collected prior to (Pre) and after two (P2), seven (P7), nine (P9), eleven (P11), and thirteen (P13) sessions, always 96 hours after last session. The reference change values (RCV) analysis was employed for comparing the responses, and the percentual differences between the serial results were calculated for each subject and compared with RCV(95%). Four subjects presented significant changes for creatine kinase at P2, and another two at P13; six for C-reactive protein at P2, and three at P11; two for neutrophils at P2, P4, and P13, respectively; and only one for white blood cells at P2, P4, P7, and P9, for lymphocyte at P7, P9, and P13, and for platelet at P4. We conclude that EO induced high magnitude of muscle damage and inflammatory responses in the initial phase of the program with subsequent attenuation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.