ArticleProceedings of the National Academy of Sciences of the United States of America2013
Evidence for participation of the methionine sulfoxide reductase repair system in plant seed longevity.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.
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Who cites it
54 citing papers in PubMed, 1 synthesis or guideline pooled it, 118 citations in OpenAlex.
- Seed Longevity in Legumes: Deeper Insights Into Mechanisms and Molecular Perspectives.Frontiers in plant science · 2022Pooled it
- Superior alleles ofNational science review · 2026Article
- Identification of the methionine sulfoxide reductase (MSR) gene family in four Triticum species and functional analysis of TaMSRB5 involved in copper stress tolerance in Arabidopsis thaliana.Plant molecular biology · 2026Article
- Molecular timekeepers: the curious alliance of redox, repair, and protective proteins in preserving seed longevity.Crop health · 2026Review
- Integrative Physiology, Transcriptome, and Metabolome Analysis Reveals Pathways and the Key GeneJournal of agricultural and food chemistry · 2025Article
- Unraveling the Mechanistic Basis for Control of Seed Longevity.Plants (Basel, Switzerland) · 2025Review
- A genome-wide association study uncovers a ZmRap2.7-ZCN9/ZCN10 module to regulate ABA signalling and seed vigour in maize.Plant biotechnology journal · 2024Article
- The association of protein-bound methionine sulfoxide with proteomic basis for aging in beech seeds.BMC plant biology · 2024Article
- Seed longevity and genome damage.Bioscience reports · 2024Review
- Review
- Does Forced Plant Maturation by Applying Herbicide with Desiccant Action Influence Seed Longevity in Soybean?Plants (Basel, Switzerland) · 2023Article
- Genome-Wide Identification and Characterization of the Msr Gene Family in Alfalfa under Abiotic Stress.International journal of molecular sciences · 2023Article
- Genome damage accumulated in seed ageing leads to plant genome instability and growth inhibition.The Biochemical journal · 2023Article
- Raffinose family oligosaccharides (RFOs): role in seed vigor and longevity.Bioscience reports · 2022Review
- Seed DNA damage responses promote germination and growth inProceedings of the National Academy of Sciences of the United States of America · 2022Article
- Are Methionine Sulfoxide-Containing Proteins Related to Seed Longevity? A Case Study ofPlants (Basel, Switzerland) · 2022Article
- The Seed and the Metabolism Regulation.Biology · 2022Review
- A New Role for Plastid Thioredoxins in Seed Physiology in Relation to Hormone Regulation.International journal of molecular sciences · 2021Article
- Identification of a major-effect QTL associated with pre-harvest sprouting in cucumber (Cucumis sativus L.) using the QTL-seq method.BMC genomics · 2021Article
- Gene co-expression analysis of tomato seed maturation reveals tissue-specific regulatory networks and hubs associated with the acquisition of desiccation tolerance and seed vigour.BMC plant biology · 2021Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Seeds are in a natural oxidative context leading to protein oxidation. Although inevitable for proper progression from maturation to germination, protein oxidation at high levels is detrimental and associated with seed aging. Oxidation of methionine to methionine sulfoxide is a common form of damage observed during aging in all organisms. This damage is reversible through the action of methionine sulfoxide reductases (MSRs), which play key roles in lifespan control in yeast and animal cells. To investigate the relationship between MSR capacity and longevity in plant seeds, we first used two Medicago truncatula genotypes with contrasting seed quality. After characterizing the MSR family in this species, we analyzed gene expression and enzymatic activity in immature and mature seeds exhibiting distinct quality levels. We found a very strong correlation between the initial MSR capacities in different lots of mature seeds of the two genotypes and the time to a drop in viability to 50% after controlled deterioration. We then analyzed seed longevity in Arabidopsis thaliana lines, in which MSR gene expression has been genetically altered, and observed a positive correlation between MSR capacity and longevity in these seeds as well. Based on our data, we propose that the MSR repair system plays a decisive role in the establishment and preservation of longevity in plant seeds.
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