Evidence map›Paper›PMID 23400940›Full record

ArticleInternational urogynecology journal2013

Long-term outcomes of vaginal mesh versus native tissue repair for anterior vaginal wall prolapse.

Michele Jonsson Funk, Anthony G Visco, Alison C Weidner, Virginia Pate, Jennifer M Wu

Abstract readComparative Study
In one paragraph

Article in International urogynecology journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. LeFort colpocleisis for recurrent pelvic organ prolapse.International urogynecology journal · 2020
    Article
  8. Article
  9. Anterior colporrhaphy: why surgeon performance is paramount.International urogynecology journal · 2014
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Michele Jonsson FunkDepartment of Epidemiology, Gillings School of Global Public Health, Chapel Hill, USA.
Anthony G Visco
Alison C Weidner
Virginia Pate
Jennifer M Wu
Duke University · US

Funding

Duke University Medical Center (DUMC) Pelvic Floor Disorders Network (PFDN) Clinical SiteUG1HD041267 · NICHD · DUKE UNIVERSITY · PI NAZEMA Y SIDDIQUI · 2016 to 2026
$2.8M
Doubly robust elimination: best practices for comparative effectiveness researchK02HS017950 · AHRQ · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JONSSON FUNK, MICHELE LAURA · 2009 to 2013
$653k
Translational Research in Pelvic Floor DisordersK23HD068404 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WU, JENNIFER M. · 2011 to 2014
$509k
AHRQ HHS K02 HS017950AHRQ HHS K02HS017950NICHD NIH HHS K23 HD068404NICHD NIH HHS K23HD068404NICHD NIH HHS UG1 HD041267
6 · The paper itself

Abstract

introduction and hypothesisTo estimate the risk of repeat surgery for recurrent prolapse or mesh removal after vaginal mesh versus native tissue repair for anterior vaginal wall prolapse.

methodsWe utilized longitudinal, adjudicated, healthcare claims from 2005 to 2010 to identify women ≥18 years who underwent an anterior colporrhaphy (CPT 57420) with or without concurrent vaginal mesh (CPT 57267). The primary outcome was repeat surgery for anterior or apical prolapse or for mesh removal/revision; these outcomes were also analyzed separately. We utilized Kaplan-Meier curves to estimate the cumulative risk of each outcome after vaginal mesh versus native tissue repair. Cox proportional hazards models were used to estimate the hazard ratio (HR) for vaginal mesh versus native tissue repair, adjusted for age, concurrent hysterectomy, and concurrent or recent sling.

resultsWe identified 27,809 anterior prolapse surgeries with 49,658 person-years of follow-up. Of those, 6,871 (24.7%) included vaginal mesh. The 5-year cumulative risk of any repeat surgery was significantly higher for vaginal mesh versus native tissue (15.2 % vs 9.8 %, p <0.0001) with a 5-year risk of mesh revision/removal of 5.9%. The 5-year risk of surgery for recurrent prolapse was similar between vaginal mesh and native tissue groups (10.4 % vs 9.3 %, p = 0.70. The results of the adjusted Cox model were similar (HR 0.93, 95%CI: 0.83, 1.05).

conclusionsThe use of mesh for anterior prolapse was associated with an increased risk of any repeat surgery, which was driven by surgery for mesh removal. Native tissue and vaginal mesh surgery had similar 5-year risks for surgery for recurrent prolapse.

Indexed as

Surgical MeshAdolescentAdultAgedAged, 80 and overFemaleFollow-Up StudiesGynecologic Surgical ProceduresHumansLongitudinal StudiesMiddle AgedProportional Hazards ModelsRecurrenceReoperationRisk FactorsTreatment Outcome

Identifiers

PMID23400940
PMCPMC3894057
OpenAlexW2026177949

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.