Evidence map›Paper›PMID 23400790›Full record

ReviewNeuropsychology review2013

Cognitive rehabilitation therapies for Alzheimer's disease: a review of methods to improve treatment engagement and self-efficacy.

Jimmy Choi, Elizabeth W Twamley

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Neuropsychology review, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06643559 (Investigating The Effect Of Cognitive Rehabilitation On Cognitive Impairment Associated With Antiseizure Medications In Patients With Epilepsy), which is not on this map. Cited by 53 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 5 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06643559 nacompletednot on this mapstarted 2022, after this paper: background citation

Investigating The Effect Of Cognitive Rehabilitation On Cognitive Impairment Associated With Antiseizure Medications In Patients With Epilepsy

TypeinterventionalSponsorGulhane Training and Research HospitalRan2022 to 2023Enrolled368ConditionsCognitive Dysfunction, EpilepsyArmscognitive rehabilitation
3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 5 syntheses or guidelines pooled it, 187 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  5. Pooled it
  6. Comparative Efficacy of Active Group Music Intervention versus Group Music Listening in Alzheimer's Disease.International journal of environmental research and public health · 2021
    Trial
  7. Trial
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  9. Cognitive training in Alzheimer's disease: a controlled randomized study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2017
    Trial
  10. Trial
  11. Trial
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  13. The effectiveness of reality orientation in the treatment of Alzheimer's disease.American journal of Alzheimer's disease and other dementias · 2015
    Trial
  14. Trial
  15. Article
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Jimmy ChoiMental Health Services & Policy Research, Columbia University Medical Center, 1051 Riverside Dr, Mailbox 100, New York, NY 10032, USA. jc3110@columbia.edu
Elizabeth W Twamley
Columbia University Irving Medical Center · USUniversity of California, San Diego · US

Funding

Intrinsic Motivation and Learning in SchizophreniaK23MH086755 · NIMH · HARTFORD HOSPITAL · PI CHOI, JIMMY · 2011 to 2015
$895k
NIMH NIH HHS K23 MH086755
6 · The paper itself

Abstract

Cognitive rehabilitation therapies for Alzheimer's disease (AD) are becoming more readily available to the geriatric population in an attempt to curb the insidious decline in cognitive and functional performance. However, people with AD may have difficulty adhering to these cognitive treatments due to denial of memory deficits, compromised brain systems, cognitive incapacity for self-awareness, general difficulty following through on daily tasks, lack of motivation, hopelessness, and apathy, all of which may be either due to the illness or be secondary to depression. Cognitive rehabilitation training exercises are also labor intensive and, unfortunately, serve as a repeated reminder about the memory impairments and attendant functional consequences. In order for cognitive rehabilitation methods to be effective, patients must be adequately engaged and motivated to not only begin a rehabilitation program but also to remain involved in the intervention until a therapeutic dosage can be attained. We review approaches to cognitive rehabilitation in AD, neuropsychological as well as psychological obstacles to effective treatment in this population, and methods that target adherence to treatment and may therefore be applicable to cognitive rehabilitation therapies for AD. The goal is to stimulate discussion among researchers and clinicians alike on how treatment effects may be mediated by engagement in treatment, and what can be done to enhance patient adherence for cognitive rehabilitation therapies in order to obtain greater cognitive and functional benefits from the treatment itself.

Indexed as

MotivationSelf EfficacyActivities of Daily LivingAlzheimer DiseaseApathyHumansNeuropsychological Tests

Identifiers

PMID23400790
PMCPMC3596462
OpenAlexW2011209707

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.