ArticleRheumatology international2013
Erosive and inflammatory joint changes in hereditary hemochromatosis arthropathy detected by low-field magnetic resonance imaging.
Article in Rheumatology international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Hemochromatosis osteoarthritis.Frontiers in endocrinology · 2026Review
- Clinical and imaging features of haemochromatosis arthropathy: a systematic literature review and meta-analysis to inform the development of EULAR classification criteria.EULAR rheumatology open · 2025Article
- Overview of Ankle Arthropathy in Hereditary Hemochromatosis.Medical sciences (Basel, Switzerland) · 2023Review
- Analysis of Hand Joint Space Morphology in Women and Men with Hereditary Hemochromatosis.Calcified tissue international · 2023Article
- Ultrasound verified inflammation and structural damage in patients with hereditary haemochromatosis-related arthropathy.Arthritis research & therapy · 2017Article
- T2 black lesions on routine knee MRI: differential considerations.European radiology · 2016Review
- HFE-related hemochromatosis: an update for the rheumatologist.Current rheumatology reports · 2014Review
Corrections and comments
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Authors and funding
3 authors.
Funding
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Abstract
The aim of the article is to describe and characterize the hemochromatosis arthropathy of the hand by low-field MRI in symptomatic and asymptomatic patients. Forty-nine patients with hereditary hemochromatosis (37 with and twelve without arthropathy) were examined clinically and by low-field MRI of the hands. The examination showed heterogeneous degenerative and inflammatory joint changes such as erosions (in 84% of all symptomatic patients), synovitis (77%), bone marrow edema (38%), subchondral cysts (30%), tenosynovitis (30%), joint space narrowing (73%) and osteophytes (59%) including hook-shaped osteophytes at MCP joints (32%). Mild joint changes were also seen in a lower percentage of asymptomatic patients. This is the first larger study addressing the joint changes of the hand in hereditary hemochromatosis using low-field MRI. Our study emphasizes the inflammatory and destructive character of the arthropathy besides the well-known degenerative joint changes described in conventional X-ray. The impact of joint changes in asymptomatic patients deserves further investigation.
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