ArticleBiomarker insights2013
Lipid profile of patients with acute myocardial infarction and its correlation with systemic inflammation.
Article in Biomarker insights, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Relationship between Hyperlipidemia, Cardiovascular Disease and Stroke: A Systematic Review.Current cardiology reviews · 2021Pooled it
- Adipokine-mediated metabolic responses across BMI in acute myocardial infarction.BMC cardiovascular disorders · 2026Article
- Bootstrap-Augmented Analysis of Non-Linear Associations Between Glucose, hsCRP, and First Myocardial Infarction in a Cardiovascular Population.International journal of molecular sciences · 2026Article
- Factors associated with low-density lipoprotein control in outpatients with myocardial infarction: A hospital-based study.PloS one · 2026Article
- Effects of intensive rosuvastatin on ventricular remodeling and cardiac function in elderly patients with STEMI undergoing PCI.Frontiers in cardiovascular medicine · 2025Article
- Cleistopholis patens root bark extract exerts cardioprotective effect against doxorubicin-induced myocardial toxicity in rats.Laboratory animal research · 2024Article
- Review
- Redox Status and Telomere-Telomerase System Biomarkers in Patients with Acute Myocardial Infarction Using a Principal Component Analysis: Is There a Link?International journal of molecular sciences · 2023Article
- Longitudinal association between positive affect and blood lipids in patients following acute myocardial infarction.PloS one · 2023Article
- Serum Levels of Proinflammatory Biomarkers in Military Recruits with and without Metabolic Syndrome.Mediators of inflammation · 2023Article
- Association of myocardial infarction and angina pectoris with obesity and biochemical indices in the South Korean population.Scientific reports · 2022Article
- Cardiac biomarkers and detection methods for myocardial infarction.Molecular & cellular toxicology · 2022Review
- A nonlinear association of total cholesterol with all-cause and cause-specific mortality.Nutrition & metabolism · 2021Article
- Article
- Estimation of apolipoprotein A in early onset ST-segment elevation myocardial infarction.Cardiovascular endocrinology & metabolism · 2019Article
- Association between plasma lipid levels during acute coronary syndrome and long-term malignancy risk. The ABC-4* study on heart disease.BMC cardiovascular disorders · 2019Article
- Article
- A Control-Theoretic Model of Atherosclerosis.International journal of molecular sciences · 2019Article
- Association of change in total cholesterol level with mortality: A population-based study.PloS one · 2018Article
- Potential of lipoproteins as biomarkers in acute myocardial infarction.Anatolian journal of cardiology · 2017Review
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The biomarker potential of using various lipids fractions for predicting risk of acute myocardial infarction (AMI) is controversial. We therefore compared the lipid profiles, including serum total cholesterol (TC), low-density lipoprotein cholesterol (LDL), high-density lipoprotein cholesterol (HDL) and triglycerides (TG), in 67 AMI patients. Patients included 28 STEMI (ST-elevated myocardial infarction) patients, 39 NSTEMI (non-ST-elevated myocardial infarction) patients and 25 patients with chest pain. Control group included 54 age- and gender-matched normal subjects. We also studied the correlation between lipid profile and systemic inflammation in these subjects. There were significant decreases in TC, LDL and HDL levels in both STEMI and NSTEMI patients as compared to normal subjects; however, patients with chest pain did not show any significant change in these lipids. Serum TG levels did not differ significantly among the study groups. There were significant increases in serum high-sensitive C-reactive protein (hs-CRP) levels in STEMI and NSTEMI patients, as compared to control group. Serum hs-CRP showed significant inverse correlation with HDL; however, hs-CRP was not correlated with TC, LDL, and TG. In conclusion, our findings suggest that reduction in serum TC does not prevent the risk of AMI, whereas a decrease in serum HDL and increase in hs-CRP strongly predisposes the risky individuals to an AMI event. We emphasize the importance of HDL and CRP measurements for the assessment of a combined lipid-inflammation risk factor that could be a useful predictor of high risk individuals, as well as a prognostic marker in AMI patients.
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