Neurodegenerative disease: altered DNA methylation and RNA splicing could be key mechanisms in Huntington disease.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

9 citing papers in PubMed.

1. DNA methylation of microRNA-365-1 induces apoptosis of hair follicle stem cells by targetingNon-coding RNA research · 2024
   Article
2. Neuroinflammation and the role of epigenetic-based therapies for Huntington's disease management: the new paradigm.Inflammopharmacology · 2024
   Review
3. DNA Methylation: A Promising Approach in Management of Alzheimer's Disease and Other Neurodegenerative Disorders.Biology · 2022
   Review
4. Role of DNMTs in the Brain.Advances in experimental medicine and biology · 2022
   Review
5. Epigenomic Remodeling in Huntington's Disease-Master or Servant?Epigenomes · 2020
   Review
6. DNA methylation age-acceleration is associated with disease duration and age at onset in C9orf72 patients.Acta neuropathologica · 2017
   Article
7. Axonal Degeneration during Aging and Its Functional Role in Neurodegenerative Disorders.Frontiers in neuroscience · 2017
   Review
8. The epigenetics of aging and neurodegeneration.Progress in neurobiology · 2015
   Review
9. Epigenetic mechanisms of neurodegeneration in Huntington's disease.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2013
   Review

Corrections and comments

• Comment on
  Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease.2013
• Comment on
  Extensive changes in DNA methylation are associated with expression of mutant huntingtin.2013

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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