Evidence map›Paper›PMID 23398935›Full record

ArticleInfluenza and other respiratory viruses2013

The first, second and third wave of pandemic influenza A (H1N1)pdm09 in North Denmark Region 2009-2011: a population-based study of hospitalizations.

Iben Ørsted, Mette Mølvadgaard, Hans Linde Nielsen, Henrik Nielsen

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Article in Influenza and other respiratory viruses, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

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10citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
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  5. Article
  6. Article
  7. Article
  8. Observational
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

4 authors.

Iben ØrstedDepartment of Infectious Diseases, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark. iben.oersted@rn.dk
Mette Mølvadgaard
Hans Linde Nielsen
Henrik Nielsen

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesDenmark experienced three waves of the new pandemic influenza A (H1N1)pdm09 from July 2009 to February 2011. The aim of the study was to describe the epidemiology and clinical characteristics of hospitalized patients in a defined population of North Denmark Region with a mixed urban and rural community of 579,000 inhabitants.

methodsReview of medical records of all hospitalized patients with confirmed influenza A from July 2009 to February 2011.

resultsTwo hundred and seventy-three patients were admitted to hospital. The age-related population incidences of hospitalization were as follows: 0-14 years: 111/100,000, 15-64 years: 39/100,000, and ≥ 65 years: 17/100,000. During the first wave (July 2009-August 2009), three patients were admitted - none received treatment in intensive care units (ICUs), during the second wave (October 2009-January 2010), 158 patients were admitted - nine received treatment in ICUs, and during the third wave (December 2010-February 2011), 112 patients were admitted - 25 received treatment in ICUs. Fourteen patients (5%) died within 30 days of diagnosis (median 55 years; range 14-76 years) and additional seven patients (2.6%) died within 365 days (median 25 years; range 1-86 years).

conclusionsPatients hospitalized with pandemic influenza A (H1N1)pdm09 were predominantly children and younger adults, and only a few patients were >65 years. The third wave was the most severe taking the number and percentage of patients admitted to ICUs and 30-day mortality into consideration. We observed that the incidence of hospitalizations as well as clinical severity among younger adults did not decline from the second to the third wave.

Indexed as

AdolescentAdultAgedAged, 80 and overChildChild, PreschoolDenmarkFemaleHospitalizationHumansIncidenceInfantInfluenza A Virus, H1N1 SubtypeInfluenza, HumanIntensive Care UnitsMaleEpidemiologyhospitalizationICUinfluenzaoutcomepandemic

Identifiers

PMID23398935
PMCPMC5781212

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.