ArticleGenes, brain, and behavior2013
Drosophila social clustering is disrupted by anesthetics and in narrow abdomen ion channel mutants.
Article in Genes, brain, and behavior, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 43 citations in OpenAlex.
- Sociability is a Multidimensional Trait in Drosophila melanogaster.Behavior genetics · 2026Article
- Stress-induced reduction of sodium leak currents causes social deficits by impairing dorsal dentate gyrus-medial septum glutamatergic projection.Molecular psychiatry · 2025Article
- Neuroligin 3 highlights sexually dimorphic circuitry in Drosophila social spacing.bioRxiv : the preprint server for biology · 2025Article
- Movement and Dispersion Parameters Characterizing the Group Behavior ofAnimals : an open access journal from MDPI · 2025Article
- Reynolds rules in swarm fly behavior based on KAN transformer tracking method.Scientific reports · 2025Article
- The Drosophila adult brain: short overview of structure, function, and resources Graphical Review Paper.Current research in insect science · 2025Review
- Juvenile hormone as a key regulator for asymmetric caste differentiation in ants.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Recovery from social isolation requires dopamine in males, but not the autism-related geneRoyal Society open science · 2024Article
- DVT: a high-throughput analysis pipeline for locomotion and social behavior in adult Drosophila melanogaster.Cell & bioscience · 2023Article
- Distinct decision-making properties underlying the species specificity of group formation of flies.Royal Society open science · 2022Article
- A screen for sleep and starvation resistance identifies a wake-promoting role for the auxiliary channel unc79.G3 (Bethesda, Md.) · 2021Article
- Inheritance of pheromone profiles from agedmicroPublication biology · 2021Article
- Social attraction in Drosophila is regulated by the mushroom body and serotonergic system.Nature communications · 2020Article
- Article
- Traumatic injury in female Drosophila melanogaster affects the development and induces behavioral abnormalities in the offspring.Behavioral and brain functions : BBF · 2019Article
- A Genetic Toolkit for Dissecting Dopamine Circuit Function in Drosophila.Cell reports · 2018Article
- Progeny of old parents have increased social space in Drosophila melanogaster.Scientific reports · 2018Article
- Modulation of social space by dopamine inBiology letters · 2017Article
- Conditions Affecting Social Space in Drosophila melanogaster.Journal of visualized experiments : JoVE · 2015Article
- Drosophila mutants of the autism candidate gene neurobeachin (rugose) exhibit neuro-developmental disorders, aberrant synaptic properties, altered locomotion, and impaired adult social behavior and activity patterns.Journal of neurogenetics · 2015Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Members of many species tend to congregate, a behavioral strategy known as local enhancement. Selective advantages of local enhancement range from efficient use of resources to defense from predators. While previous studies have examined many types of social behavior in fruit flies, few have specifically investigated local enhancement. Resource-independent local enhancement (RILE) has recently been described in the fruit fly using a measure called social space index (SSI), although the neural mechanisms remain unknown. Here, we analyze RILE of Drosophila under conditions that allow us to elucidate its neural mechanisms. We have investigated the effects of general volatile anesthetics, compounds that compromise higher order functioning of the type typically required for responding to social cues. We exposed Canton-S flies to non-immobilizing concentrations of halothane and found that flies had a significantly decreased SSI compared with flies tested in air. Narrow abdomen (na) mutants, which display altered responses to anesthetics in numerous behavioral assays, also have a significantly reduced SSI, an effect that was fully reversed by restoring expression of na by driving a UAS-NA rescue construct with NA-GAL4. We found that na expression in cholinergic neurons fully rescued the behavioral defect, whereas expression of na in glutamatergic neurons did so only partially. Our results also suggest a role for na expression in the mushroom bodies (MBs), as suppressing na expression in the MBs of NA-GAL4 rescue flies diminishes SSI. Our data indicate that RILE, a simple behavioral strategy, requires complex neural processing.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.