Evidence map›Paper›PMID 23398433›Full record

ArticleBehavioral neuroscience2013

Frontal and posterior subtypes of neuropsychological deficit in Parkinson's disease.

Ivy N Miller, Sandy Neargarder, Megan M Risi, Alice Cronin-Golomb

Erratum issued Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Behavioral neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT06483126 (The Benefits of Nature for Mood and Cognition in Persons With and Without Parkinson's Disease), which is not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06483126 completednot on this mapstarted 2024, after this paper: background citation

The Benefits of Nature for Mood and Cognition in Persons With and Without Parkinson's Disease

TypeobservationalSponsorBoston University Charles River CampusRan2024 to 2025Enrolled97ConditionsParkinson Disease, Mood, Cognition
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. N200 and P300 component changes in Parkinson's disease: a meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Salience and Default Mode Network Coupling Predicts Cognition in Aging and Parkinson's Disease.Journal of the International Neuropsychological Society : JINS · 2016
    Article
  15. The Therapeutic Potential of Exercise to Improve Mood, Cognition, and Sleep in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2016
    Review
  16. Article
  17. Article
  18. The effect of Parkinson's disease subgroups on verbal and nonverbal fluency.Journal of clinical and experimental neuropsychology · 2014
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ivy N MillerDepartment of Psychology.
Sandy NeargarderDepartment of Psychology.
Megan M RisiDepartment of Psychology, Bridgewater State University.
Alice Cronin-GolombDepartment of Psychology.
Bridgewater State University · US

Funding

Effects of Parkinson's Disease on Perception, Cognition, and GaitR01NS067128 · NINDS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI CRONIN-GOLOMB, ALICE · 2009 to 2013
$3.2M
NINDS NIH HHS R01 NS067128NINDS NIH HHS R01NS067128
6 · The paper itself

Abstract

Mild cognitive impairment in Parkinson's disease (PD) is heterogeneous in regard to affected domains. Although patterns of cognitive performance that may predict later dementia are as yet undetermined, posterior- versus frontal-type assessments show promise for differential predictive value. The present study included 70 individuals: 42 with idiopathic PD without dementia and 28 age- and education-matched healthy control adults (HC). Participants completed assessments of cognition with emphasis on tests that are sensitive to frontal and posterior deficits. PD patients were classified into cognitive subgroups and the subgroups were compared on demographic and disease variables. Individual performance across neuropsychological tests was evaluated for the PD group. Patients with PD performed more poorly than HC on several measures of cognition, and they were classified into frontal (12), posterior (3), both (10) and neither subgroups (17), the latter two in reference to frontal- and posterior-type deficits. The neither subgroup was distinguished by less motor impairment than the both subgroup, but the four subgroups did not otherwise differ on demographic or disease variables. Across patients, the tests most sensitive to cognitive impairment included measures of attention and executive functioning (frontal-type tests). Examination of individual test performance for PD revealed substantial heterogeneity across tests with respect to number and severity of deficits. The current study provides insight into which commonly used neuropsychological tests are most sensitive to cognitive deficits (strictly defined) in a nondemented, well characterized PD sample, and into the relation of cognitive subgroups to demographic and disease-specific variables.

Indexed as

AttentionExecutive FunctionProblem SolvingAgedCognition DisordersFemaleHumansMaleMiddle AgedNeuropsychological TestsParkinson Disease

Identifiers

PMID23398433
PMCPMC3819031
OpenAlexW1963924677

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.