Evidence map›Paper›PMID 23398227›Full record

Trial reportThe American journal on addictions2013

Major depression and PTSD in pregnant smokers enrolled in nicotine gum treatment trial.

Ellen Dornelas, Cheryl Oncken, John Greene, Heather Z Sankey, Henry R Kranzler

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The American journal on addictions, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Nicotine replacement therapy versus control for smoking cessation.The Cochrane database of systematic reviews · 2018
    Pooled it
  2. Pooled it
  3. Examination of the Wisconsin Inventory of Smoking Dependence Motives (WISDM-68) Factor Structure in a Sample of Pregnant Smokers.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

Ellen DornelasDepartment of Medicine, University of Connecticut School of Medicine, Farmington, Connecticut, USA. edornel@harthosp.org
Cheryl Oncken
John Greene
Heather Z Sankey
Henry R Kranzler
Baystate Medical Center · USHartford Hospital · USUConn Health · USUniversity of Connecticut · USVA Healthcare-VISN 4 · US

Funding

ZONISAMIDE VERSUS PLACEBOM01RR006192 · NCRR · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI LAURENCIN, CATO T. · 1994 to 2008
$22.1M
Nicotine Replacement Treatment for Pregnant SmokersR01DA015167 · NIDA · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI ONCKEN, CHERYL ANN · 2002 to 2006
$1.7M
Novel Approaches to Alcoholism Pharmacotherapy and RiskK24AA013736 · NIAAA · UNIVERSITY OF PENNSYLVANIA · PI KRANZLER, HENRY RICHARD · 2002 to 2012
$1.5M
NCRR NIH HHS M01 RR006192NIAAA NIH HHS K24 AA013736NIDA NIH HHS R01 DA015167NIDA NIH HHS R01 DA15167
6 · The paper itself

Abstract

BACKGROUND AND

objectivesPregnant women face considerable barriers to smoking cessation. The purpose of this study was to determine the prevalence of major depressive disorder (MDD) and post-traumatic stress disorder (PTSD) and response to smoking cessation treatment in pregnant smokers participating in a randomized, placebo-controlled trial of nicotine gum.

methodsParticipants were 194 low-income, ethnically diverse pregnant smokers.

resultsUtilizing a structured interview, 45% and 18% of the subjects met criteria for a lifetime diagnosis of MDD and PTSD, respectively. There was no difference in response to treatment, based on the presence of either of these psychiatric disorders.

conclusionsCumulatively, these findings provide evidence of the high degree of unmet mental health needs in pregnant smokers. SCIENTIFIC SIGNIFICANCE: Pregnant women with a history of MDD and PTSD appear to be as likely to benefit from smoking cessation treatment as those without such a history.

Indexed as

Tobacco Use Cessation DevicesAdultFemaleHispanic or LatinoHumansMajor Depressive DisorderPregnancyPregnancy ComplicationsPrevalenceSmokingStress Disorders, Post-Traumatic

Identifiers

PMID23398227
PMCPMC4528971
OpenAlexW2169645068

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.