ArticleMethods in molecular biology (Clifton, N.J.)2013
Assessment of CD4(+) and CD8 (+) T cell responses using MHC class I and II tetramers.
Article in Methods in molecular biology (Clifton, N.J.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Exploring Immune Responses to SARS-CoV-2: Insights from Sinopharm (BBIBP-CorV)-Vaccinated Individuals in a Group of Venezuelan Admixed Volunteers.Biomedicines · 2025Article
- A vaccine platform targeting lung-resident memory CD4Nature communications · 2024Article
- Predicting TCR sequences for unseen antigen epitopes using structural and sequence features.Briefings in bioinformatics · 2024Article
- Can we predict T cell specificity with digital biology and machine learning?Nature reviews. Immunology · 2023Review
- Tumour neoantigen mimicry by microbial species in cancer immunotherapy.British journal of cancer · 2021Review
- Murine cytomegalovirus dissemination but not reactivation in donor-positive/recipient-negative allogeneic kidney transplantation can be effectively prevented by transplant immune tolerance.Kidney international · 2020Article
- cGAS-mediated control of blood-stage malaria promotes Plasmodium-specific germinal center responses.JCI insight · 2018Article
- Detecting Antigen-Specific T Cell Responses: From Bulk Populations to Single Cells.International journal of molecular sciences · 2015Review
- Characteristics of γδ T cells in Schistosoma japonicum-infected mouse mesenteric lymph nodes.Parasitology research · 2014Article
- Use of "one-pot, mix-and-read" peptide-MHC class I tetramers and predictive algorithms to improve detection of cytotoxic T lymphocyte responses in cattle.Veterinary research · 2014Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The low frequency of T cells specific for given antigens makes the study of antigen-specific T cell responses difficult. The development of MHC class I and II tetramer staining techniques allows precise quantification and tracking of antigen-specific CD8(+) and CD4(+) T cell responses. Here, we describe a protocol for MHC class I and II tetramer staining of mouse T cells isolated from various tissues of mice infected with lymphocytic choriomeningitis virus (LCMV) or with murine cytomegalovirus (MCMV).
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Registered trials
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