ArticleBehavior genetics2013
Genotype by environment interactions in cognitive ability: a survey of 14 studies from four countries covering four age groups.
Article in Behavior genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- The causal arrows from genotype, environment, and management to plant phenotype are double headed.Journal of experimental botany · 2025Review
- Many roads to a gene-environment interaction.American journal of human genetics · 2024Review
- Data Harmonization in Aging Research: Not so Fast.Experimental aging research · 2015Article
- Environment-by-PGS Interaction in the Classical Twin Design: An Application to Childhood Anxiety and Negative Affect.Multivariate behavioral researchArticle
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
A large part of the variation in cognitive ability is known to be due to genetic factors. Researchers have tried to identify modifiers that influence the heritability of cognitive ability, indicating a genotype by environment interaction (G×E). To date, such modifiers include measured variables like income and socioeconomic status. The present paper focuses on G×E in cognitive ability where the environmental variable is an unmeasured environmental factor that is uncorrelated in family members. We examined this type of G×E in the GHCA-database (Haworth et al., Behav Genet 39:359-370, 2009), which comprises data of 14 different cognition studies from four different countries including participants of different ages. Results indicate that for younger participants (4-13 years), the strength of E decreases across the additive genetic factor A, but that this effect reverts for older participants (17-34 years). However, a clear and general conclusion about the presence of a genuine G×E is hampered by differences between the individual studies with respect to environmental and genetic influences on cognitive ability.
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Registered trials
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