Evidence map›Paper›PMID 23396542›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA

Evaluating standard terminologies for encoding allergy information.

Foster R Goss, Li Zhou, Joseph M Plasek, Carol Broverman, George Robinson, Blackford Middleton, Roberto A Rocha

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Article
  6. AllergyMap: An Open Source Corpus of Allergy Mention Normalizations.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2020
    Article
  7. Article
  8. Article
  9. Article
  10. Clinical Concept Value Sets and Interoperability in Health Data Analytics.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2018
    Article
  11. Food entries in a large allergy data repository.Journal of the American Medical Informatics Association : JAMIA · 2016
    Article
  12. Article
  13. Article
  14. Article
  15. Automated identification of drug and food allergies entered using non-standard terminology.Journal of the American Medical Informatics Association : JAMIA
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Foster R GossClinical Informatics Research & Development, Partners HealthCare System, Inc., Wellesley, Massachusetts, USA.
Li Zhou
Joseph M Plasek
Carol Broverman
George Robinson
Blackford Middleton
Roberto A Rocha
Mass General Brigham · USBrigham and Women's Hospital · USFirst Data (United States) · USHarvard University · US

Funding

RESEARCH TRAINING-MEDICAL INFORMATICS 90T15LM007092 · NLM · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI Nils Gehlenborg · 1992 to 2026
$32.8M
NLM NIH HHS T15 LM007092NLM NIH HHS T15- LM007092
6 · The paper itself

Abstract

objectiveAllergy documentation and exchange are vital to ensuring patient safety. This study aims to analyze and compare various existing standard terminologies for representing allergy information.

methodsFive terminologies were identified, including the Systemized Nomenclature of Medical Clinical Terms (SNOMED CT), National Drug File-Reference Terminology (NDF-RT), Medication Dictionary for Regulatory Activities (MedDRA), Unique Ingredient Identifier (UNII), and RxNorm. A qualitative analysis was conducted to compare desirable characteristics of each terminology, including content coverage, concept orientation, formal definitions, multiple granularities, vocabulary structure, subset capability, and maintainability. A quantitative analysis was also performed to compare the content coverage of each terminology for (1) common food, drug, and environmental allergens and (2) descriptive concepts for common drug allergies, adverse reactions (AR), and no known allergies.

resultsOur qualitative results show that SNOMED CT fulfilled the greatest number of desirable characteristics, followed by NDF-RT, RxNorm, UNII, and MedDRA. Our quantitative results demonstrate that RxNorm had the highest concept coverage for representing drug allergens, followed by UNII, SNOMED CT, NDF-RT, and MedDRA. For food and environmental allergens, UNII demonstrated the highest concept coverage, followed by SNOMED CT. For representing descriptive allergy concepts and adverse reactions, SNOMED CT and NDF-RT showed the highest coverage. Only SNOMED CT was capable of representing unique concepts for encoding no known allergies.

conclusionsThe proper terminology for encoding a patient's allergy is complex, as multiple elements need to be captured to form a fully structured clinical finding. Our results suggest that while gaps still exist, a combination of SNOMED CT and RxNorm can satisfy most criteria for encoding common allergies and provide sufficient content coverage.

Indexed as

Vocabulary, ControlledHumansHypersensitivitySystematized Nomenclature of MedicineTerminology as TopicAllergyDrug IntoleranceHypersensitivityStandardsTerminologyVocabulary, Controlled

Identifiers

PMID23396542
PMCPMC3756252
OpenAlexW2118229857

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.