ArticleCell stem cell2013
H2A.Z sets the stage in ESCs.
Article in Cell stem cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- Gas41 links histone acetylation to H2A.Z deposition and maintenance of embryonic stem cell identity.Cell discovery · 2018Article
- Possible role of intragenic DNA hypermethylation in gene silencing of the tumor suppressor gene NR4A3 in acute myeloid leukemia.Leukemia research · 2016Article
- Article
- Developmental control of transcriptional and proliferative potency during the evolutionary emergence of animals.Developmental dynamics : an official publication of the American Association of Anatomists · 2015Article
- CAST-ChIP maps cell-type-specific chromatin states in the Drosophila central nervous system.Cell reports · 2013Article
- Gene dysregulation by histone variant H2A.Z in bladder cancer.Epigenetics & chromatin · 2013Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
ESCs undergo drastic changes in chromatin states during differentiation. Two recent papers in Cell (Li et al., 2012) and Cell Stem Cell (Hu et al., 2013) demonstrate that histone variant H2A.Z plays essential roles in this process by preconfiguring nucleosomes for depletion and recruiting transcription cofactors to cis-regulatory elements.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.