Evidence map›Paper›PMID 23395438›Full record

ArticleCell stem cell2013

SWItching on epidermal cell fate.

Carolina N Perdigoto, Evan S Bardot, Elena Ezhkova

Abstract readComment
In one paragraph

Article in Cell stem cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Actin-Like Protein 6A as an Oncogene and Therapeutic Target in Cancer.International journal of medical sciences · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Epigenetic regulation of epidermal differentiation.Cold Spring Harbor perspectives in medicine · 2014
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Carolina N PerdigotoBlack Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Evan S Bardot
Elena Ezhkova

Funding

Toward understanding the molecular mechanisms of Merkel cell fate determinationR01AR063724 · NIAMS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI EZHKOVA, ELENA · 2012 to 2021
$4.2M
Elucidating the Functions of Epigenetic Regulators in Control of Skin Stem CellsR00AR057817 · NIAMS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI EZHKOVA, ELENA · 2011 to 2013
$735k
NIAMS NIH HHS R00 AR057817NIAMS NIH HHS R01 AR063724
6 · The paper itself

Abstract

Chromatin regulatory complexes are well known regulators of stem cell fate; however, the mechanisms regulating their activity are not well understood. In this issue of Cell Stem Cell, Bao et al. (2013) show that ACTL6a inhibits targeting of the SWI/SNF complex to differentiation genes, thereby preserving the epidermal progenitor state.

Identifiers

PMID23395438
PMCPMC4454396

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.