Evidence map›Paper›PMID 23395006›Full record

Trial reportPatient education and counseling2013

Results from a randomized trial of a web-based, tailored decision aid for women at high risk for breast cancer.

Matthew P Banegas, Jennifer B McClure, William E Barlow, Peter A Ubel, Dylan M Smith, Brian J Zikmund-Fisher, Sarah M Greene, Angela Fagerlin

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Patient education and counseling, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 6 pooled it
6.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 6 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Decision aids for people facing health treatment or screening decisions.The Cochrane database of systematic reviews · 2024
    Pooled it
  3. Web-based decision aids for cancer clinical decisions: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Pooled it
  4. Decision aids for people facing health treatment or screening decisions.The Cochrane database of systematic reviews · 2017
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Trial
  8. GPs' willingness to prescribe aspirin for cancer preventive therapy in Lynch syndrome: a factorial randomised trial investigating factors influencing decisions.The British journal of general practice : the journal of the Royal College of General Practitioners · 2023
    Trial
  9. Trial
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Shared decision making and patient decision aids: knowledge, attitudes, and practices among Hawai'i physicians.Hawai'i journal of medicine & public health : a journal of Asia Pacific Medicine & Public Health · 2013
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Matthew P BanegasUniversity of Washington, Department of Health Services, Seattle, WA, USA. banegasmp@mail.nih.gov
Jennifer B McClure
William E Barlow
Peter A Ubel
Dylan M Smith
Brian J Zikmund-Fisher
Sarah M Greene
Angela Fagerlin
Center for Practical Bioethics · USKaiser Permanente Washington Health Research Institute · USCancer Research And Biostatistics · USDuke University · USSeattle University · USStony Brook University · US

Funding

Research Education About Cancer and Health (REACH) CoreU54CA132381 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Jean Alison McDougall · 2007 to 2026
$25.3M
Training / Career DevelopmentP50CA101451 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ELSTON, LAFATA J, RESNICOW, KEN A. · 2003 to 2012
$18.2M
Biobehavioral Cancer Prevention and Control Training ProgramR25CA092408 · NCI · UNIVERSITY OF WASHINGTON · PI PATRICK, DONALD LEE · 2001 to 2015
$7.1M
Training ProgramU54CA153502 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI THOMPSON, BETI · 2010 to 2015
$4.7M
NCI NIH HHS 1U54CA153502-01NCI NIH HHS P50 CA101451NCI NIH HHS R25 CA092408NCI NIH HHS R25CA092408NCI NIH HHS U54 CA132381NCI NIH HHS U54 CA153502
6 · The paper itself

Abstract

objectiveTo assess the impact of Guide to Decide (GtD), a web-based, personally-tailored decision aid designed to inform women's decisions about prophylactic tamoxifen and raloxifene use.

methodsPostmenopausal women, age 46-74, with BCRAT 5-year risk ≥ 1.66% and no prior history of breast cancer were randomized to one of three study arms:intervention (n=690), Time 1 control (n=160), or 3-month control (n=162). Intervention participants viewed GtD prior to completing a post-test and 3 month follow-up assessment. Controls did not. We assessed the impact of GtD on women's decisional conflict levels and treatment decision behavior at post-test and at 3 months, respectively.

resultsIntervention participants had significantly lower decisional conflict levels at post-test (p<0.001) and significantly higher odds of making a decision about whether or not to take prophylactic tamoxifen or raloxifene at 3-month follow-up (p<0.001) compared to control participants.

conclusionGtD lowered decisional conflict and helped women at high risk of breast cancer decide whether to take prophylactic tamoxifen or raloxifene to reduce their cancer risk. PRACTICE IMPLICATIONS: Web-based, tailored decision aids should be used more routinely to facilitate informed medical decisions, reduce patients' decisional conflict, and empower patients to choose the treatment strategy that best reflects their own values.

Indexed as

Decision Support TechniquesAgedBreast NeoplasmsConflict, PsychologicalFemaleHumansInternetMichiganMiddle AgedRaloxifene HydrochlorideRisk FactorsTamoxifenTreatment OutcomeRaloxifene HydrochlorideTamoxifen

Identifiers

PMID23395006
PMCPMC3650477
OpenAlexW2045410376

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.