Evidence map›Paper›PMID 23394941›Full record

ArticleStructure (London, England : 1993)2013

Hand-holding for retrohoming in a molecular diversity dance.

Joachim Jaeger, Marlene Belfort

Abstract readComment
In one paragraph

Article in Structure (London, England : 1993), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Joachim JaegerDivision of Genetics, Wadsworth Center, New York State Department of Health, Albany, NY 12201, USA.
Marlene Belfort

Funding

SELF-SPLICING INTEINS: FUNCTION, EVOLUTION, APPLICATIONR01GM044844 · NIGMS · WADSWORTH CENTER · PI BELFORT, MARLENE · 1990 to 2019
$8.9M
SELF-SPLICING INTRONS IN THE PHAGE T4/E COLI SYSTEMR01GM039422 · NIGMS · WADSWORTH CENTER · PI BELFORT, MARLENE · 1988 to 2019
$5.3M
INTRON DYNAMICS IN BACTERIAR37GM039422 · NIGMS · WADSWORTH CENTER · PI BELFORT, MARLENE · 2001 to 2010
$4.0M
Developing HIV-1 Nef as a novel drug targetR21AI071879 · NIAID · WADSWORTH CENTER · PI JAEGER, JOACHIM · 2008 to 2009
$395k
NIAID NIH HHS AI071879NIAID NIH HHS R21 AI071879NIGMS NIH HHS GM39422NIGMS NIH HHS GM44844NIGMS NIH HHS R01 GM039422NIGMS NIH HHS R01 GM044844NIGMS NIH HHS R37 GM039422
6 · The paper itself

Abstract

In bacterial systems, adaptive protein sequence changes can be mediated by diversity-generating retroelements in a process known as retrohoming. An accessory variability determinant (Avd), together with a reverse transcriptase (RT), is critically involved in this process. In this issue of Structure, Alayyoubi and colleagues describe the structure of Avd as a basis for interactions with RT that promote retrohoming.

Indexed as

RetroelementsBacteriophagesBordetellaRNA-Directed DNA PolymeraseViral ProteinsRetroelementsRNA-Directed DNA PolymeraseViral Proteins

Identifiers

PMID23394941
PMCPMC3638863

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.