Evidence map›Paper›PMID 23394825›Full record

Trial reportAIDS care2013

Effects of behavioral stress reduction Transcendental Meditation intervention in persons with HIV.

Sumedha Chhatre, David S Metzger, Ian Frank, Jean Boyer, Edward Thompson, Sanford Nidich, Luis J Montaner, Ravishankar Jayadevappa

Abstract readClinical Trial, Phase IComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in AIDS care, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 8 pooled it
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 8 syntheses or guidelines pooled it, 87 citations in OpenAlex.

  1. Pooled it
  2. Effectiveness of Mantra-Based Meditation on Mental Health: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Sumedha Chhatrea Department of Psychiatry, HIV/AIDS Prevention Research Division , University of Pennsylvania , Philadelphia , PA , USA.
David S Metzger
Ian Frank
Jean Boyer
Edward Thompson
Sanford Nidich
Luis J Montaner
Ravishankar Jayadevappa
University of Pennsylvania · USMaharishi International University · USThe Wistar Institute · US

Funding

Virus & Reservoirs CoreP30AI045008 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ROBERT GROSS · 1999 to 2026
$78.6M
NIAID NIH HHS P30 AI045008
6 · The paper itself

Abstract

Stress is implicated in the pathogenesis and progression of HIV. The Transcendental Meditation (TM) is a behavioral stress reduction program that incorporates mind-body approach, and has demonstrated effectiveness in improving outcomes via stress reduction. We evaluated the feasibility of implementing TM and its effects on outcomes in persons with HIV. In this community-based single blinded Phase-I, randomized controlled trial, outcomes (psychological and physiological stress, immune activation, generic and HIV-specific health-related quality of life, depression and quality of well-being) were assessed at baseline and at six months, and were compared using parametric and nonparametric tests. Twenty-two persons with HIV were equally randomized to TM intervention or healthy eating (HE) education control group. Retention was 100% in TM group and 91% in HE control group. The TM group exhibited significant improvement in vitality. Significant between group differences were observed for generic and HIV-specific health-related quality of life. Small sample size may possibly limit the ability to observe significant differences in some outcomes. TM stress reduction intervention in community dwelling adults with HIV is viable and can enhance health-related quality of life. Further research with large sample and longer follow-up is needed to validate our results.

Indexed as

DietMeditationQuality of LifeAdultFemaleFollow-Up StudiesHIV InfectionsHumansMaleMiddle AgedPatient ParticipationRisk Reduction BehaviorSingle-Blind MethodStress Disorders, Post-TraumaticStress, PsychologicalTreatment Outcome

Identifiers

PMID23394825
PMCPMC3659206
OpenAlexW2156599287

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.