Evidence map›Paper›PMID 23392245›Full record

ArticleRNA biology2013

New developments in post-transcriptional regulation of operons by small RNAs.

Divya Balasubramanian, Carin K Vanderpool

Open access · bronzeAbstract read
In one paragraph

Article in RNA biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Divya BalasubramanianDepartment of Microbiology; University of Illinois at Urbana-Champaign; Urbana, IL USA.
Carin K Vanderpool
Urbana University · US

Funding

Molecular Determinants of Regulatory Hierarchy for Bacterial Small RNAsR01GM092830 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI VANDERPOOL, CARIN K · 2010 to 2020
$2.8M
NIGMS NIH HHS 1R01 GM092830NIGMS NIH HHS R01 GM092830
6 · The paper itself

Abstract

Small regulatory RNAs (sRNAs) are influential post-transcriptional modulators of gene expression in bacteria. They regulate gene expression by base pairing to target mRNAs, leading to inhibition of translation and/or alteration of mRNA stability. Recently, several sRNAs have been discovered to regulate genes encoded in operons. In some cases, these sRNAs regulate all the genes encoded by the polycistronic mRNA (coordinate regulation) while in other cases, only a select subset of cistrons is controlled by the sRNA (discoordinate regulation). In this point of view, mechanisms of regulation and characteristics of sRNA-mRNA interactions involving polycistronic mRNAs are described. The diversity in mechanisms represented by these few characterized examples suggests that we still have much to learn about sRNA regulation of long polycistronic messages.

Indexed as

Gene Expression Regulation, BacterialOperonBase PairingGenesGenes, BacterialRNA, BacterialRNA, MessengerRNA, Small UntranslatedRNA StabilityRNA, BacterialRNA, MessengerRNA, Small UntranslatedHfqpolycistronicRyhBSgrSSpot 42translational inhibition

Identifiers

PMID23392245
PMCPMC3672274
OpenAlexW2015039594

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.