Evidence map›Paper›PMID 23392243›Full record

ReviewRNA biology2013

microRNAs in parasites and parasite infection.

Yadong Zheng, Xuepeng Cai, Janette E Bradley

Open access · bronzeAbstract readReview
In one paragraph

Review in RNA biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 131 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Extracellular vesicles and circulating nucleic acids · 2026
    Article
  5. Use of ncRNAs to Study Host Cell-Parasite Interactions.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  6. Review
  7. miR-378a-5p targeting BRAF regulates CD4Frontiers in immunology · 2025
    Article
  8. Unveiling the hemolymphatic miRNome composition of the schistosomiasis vector snailCurrent research in parasitology & vector-borne diseases · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Identification of miRNA Associated withInternational journal of molecular sciences · 2023
    Article
  17. The Molecular Mechanisms Employed by the ParasiteInternational journal of molecular sciences · 2023
    Article
  18. Article
  19. The ElusivePathogens (Basel, Switzerland) · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 3 countries.

Yadong ZhengState Key Laboratory of Veterinary Etiological Biology; Key Laboratory of Veterinary Parasitology of Gansu Province; Lanzhou Veterinary Research Institute; CAAS; Lanzhou; Gansu, China; Key Lab of New Animal Drug Project, Gansu Province; Key Lab of Veterinary Pharmaceutical Development, Ministry of Agriculture; Lanzhou Institute of Husbandry and Pharmaceutical Sciences; CAAS; Lanzhou; Gansu, China; School of Biology; University of Nottingham; Nottingham, UK.
Xuepeng Cai
Janette E Bradley
University of Nottingham · GBLanzhou City University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

miRNAs, a subclass of small regulatory RNAs, are present from ancient unicellular protozoans to parasitic helminths and parasitic arthropods. The miRNA-silencing mechanism appears, however, to be absent in a number of protozoan parasites. Protozoan miRNAs and components of their silencing machinery possess features different from other eukaryotes, providing some clues on the evolution of the RNA-induced silencing machinery. miRNA functions possibly associate with neoblast biology, development, physiology, infection and immunity of parasites. Parasite infection can alter host miRNA expression that can favor both parasite clearance and infection. miRNA pathways are, thus, a potential target for the therapeutic control of parasitic diseases.

Indexed as

RNA InterferenceAnimalsAntiparasitic AgentsEvolution, MolecularGene Expression RegulationHumansMicroRNAsParasitesParasitic DiseasesRNA, HelminthRNA, ProtozoanRNA, Small NucleolarSignal TransductionAntiparasitic AgentsMicroRNAsRNA, HelminthRNA, ProtozoanRNA, Small NucleolarhelminthmiRNAneoblastprotozoansnoRNA

Identifiers

PMID23392243
PMCPMC3672280
OpenAlexW2060678687

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.