ArticleThe Indian journal of medical research2012
Ureaplasma serovars & their antimicrobial susceptibility in patients of infertility & genital tract infections.
Article in The Indian journal of medical research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 27 citations in OpenAlex.
- The Impact of Intrauterine Devices on the Risk of Ureaplasma Species Overgrowth: A Review of the Literature.Cureus · 2025Review
- Comprehensive Assessment of Genital Infections and Reproductive Health in Women Visiting a Fertility Clinic in Warangal, India-A Case-Control Study.Health science reports · 2025Article
- An overview regarding the relationship between Mollicutes, infertility and antibiotic resistance (Review).Biomedical reports · 2024Review
- The prevalence of Mycoplasma hominis in Outpatients at a Tertiary Care Hospital in East India.Cureus · 2022Article
- Genital Mycoplasmas and Biomarkers of Inflammation and Their Association With Spontaneous Preterm Birth and Preterm Prelabor Rupture of Membranes: A Systematic Review and Meta-Analysis.Frontiers in microbiology · 2022Review
- Epidemiological investigation and antimicrobial susceptibility analysis of mycoplasma in patients with genital manifestations.Journal of clinical laboratory analysis · 2020Article
- Mollicutes antibiotic resistance profile and presence of genital abnormalities in couples attending an infertility clinic.The Journal of international medical research · 2020Article
- Detection ofInfectious diseases in obstetrics and gynecology · 2020Article
- Hyperammonemia Post Lung Transplantation: A Review.Clinical medicine insights. Circulatory, respiratory and pulmonary medicine · 2020Review
- Recent advances in cultivation-independent molecular-based techniques for the characterization of vaginal eubiosis and dysbiosis.Faculty reviews · 2020Review
- Detection of Ureaplasma spp. serovars in genital tract of infertile males.Journal of clinical laboratory analysis · 2019Article
- Antibiotic Resistance among Clinical Ureaplasma Isolates Recovered from Neonates in England and Wales between 2007 and 2013.Antimicrobial agents and chemotherapy · 2016Article
- Antimicrobial Susceptibility Patterns of Ureaplasma urealyticum and Mycoplasma hominis Isolated From Pregnant Women.Iranian Red Crescent medical journal · 2015Article
- Colonization of the lower urogenital tract with Ureaplasma parvum can cause asymptomatic infection of the upper reproductive system in women: a preliminary study.Archives of gynecology and obstetrics · 2014Article
- Antimicrobial susceptibility patterns of Ureaplasma species and Mycoplasma hominis in pregnant women.BMC infectious diseases · 2014Article
- Prevalence of genital mycoplasma in patients with genital tract infection attending a tertiary care hospital in South India.Indian journal of sexually transmitted diseases and AIDSArticle
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND &
objectivesUreaplasmas have been implicated in a variety of clinical conditions. However, only certain serovars of ureaplasmas are disease associated. Only a few classes of antimicrobial agents are available for the treatment of mycoplasmal infections in humans. Increase of resistance of genital mycoplasmas to antimicrobials has been reported worldwide. The aim of the present study was to determine the occurrence of Ureaplasma serovars in patients with infertility and genital tract infections with polymerase chain reaction (PCR)-based serotyping. The antimicrobial susceptibilities of Ureaplasma spp. and Mycoplasma hominis were also assessed to determine the most suitable treatment strategy.
methodsSexually active adults (n=147) with symptoms of genital tract infections and 115 infertile women were enrolled. Endocervical swabs from women and urethral swabs from men were subjected to culture and multiplex PCR for detection of genital mycoplasmas. Serotyping of Ureaplasma was done by PCR and antimicrobial susceptibility to doxycycline, azithromycin, josamycin and ofloxacin was done by microbroth dilution method.
resultsUreaplasma was detected in 25.8 per cent patients with genital tract infections and 20.8 per cent in infertile women. Serovar 3/14 was the most frequent isolate followed by serovar 1 and serovar 6. The majority of Ureaplasma isolates were susceptible to doxycycline (91%) and josamycin (86%) followed by ofloxacin (77%) and azithromycin (71%). All the isolates of M. hominis were uniformly susceptible to doxycycline, josamycin and ofloxacin. INTERPRETATION &
conclusionsThe predominance of Ureaplasma serovar 3/14 suggests their possible pathogenic role in genital tract infections and infertility. For empirical treatment, doxycycline could be the drug of choice for genital mycoplasmas.
Indexed as
Identifiers
23391795PMC3612329W2118745909What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.