Evidence map›Paper›PMID 23391728›Full record

Trial reportThe British journal of psychiatry : the journal of mental science2013

Personalised intervention for people with depression and severe COPD.

George S Alexopoulos, Dimitris N Kiosses, Jo Anne Sirey, Dora Kanellopoulos, Richard S Novitch, Samiran Ghosh, Joanna K Seirup, Patrick J Raue

Registry-linked trialOpen access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The British journal of psychiatry : the journal of mental science, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00151372 (Treatment Effectiveness in Depressed Patients With Chronic Obstructive Pulmonary Disease), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00151372 nacompletednot on this map

Treatment Effectiveness in Depressed Patients With Chronic Obstructive Pulmonary Disease

TypeinterventionalSponsorWeill Medical College of Cornell UniversityRan2002 to 2008Enrolled141ConditionsPulmonary Disease, Chronic Obstructive, Major DepressionArmsTreatment Adherence Intervention, Enhanced Care
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Two Interventions for PatientsWith Major Depression and Severe Chronic Obstructive Pulmonary Disease: Impact on Quality of Life.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2019
    Trial
  3. Two Interventions for Patients with Major Depression and Severe Chronic Obstructive Pulmonary Disease: Impact on Dyspnea-Related Disability.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2018
    Trial
  4. Two Behavioral Interventions for Patients with Major Depression and Severe COPD.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2016
    Trial
  5. Trial
  6. Trial
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Models of care for late-life depression of the medically ill: examples from chronic obstructive pulmonary disease and stroke.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2015
    Article
  13. Depression and anxiety in patients with COPD.European respiratory review : an official journal of the European Respiratory Society · 2014
    Review
  14. Review
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

George S AlexopoulosWeill Cornell Medical Center, 21 Bloomingdale Road, White Plains, NY 10605, USA. gsalexop@med.cornell.edu
Dimitris N Kiosses
Jo Anne Sirey
Dora Kanellopoulos
Richard S Novitch
Samiran Ghosh
Joanna K Seirup
Patrick J Raue
Cornell University · USBurke Rehabilitation Hospital · US

Funding

Research Methods CoreP30MH085943 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI ALEXOPOULOS, GEORGE S · 2009 to 2013
$9.2M
Cornell ACISR for Late Life DepressionP30MH068638 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI ALEXOPOULOS, GEORGE S · 2003 to 2007
$6.5M
Treating Older Patients with Major Depression and Severe COPDR01MH076829 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI ALEXOPOULOS, GEORGE S · 2008 to 2012
$1.9M
NIMH NIH HHS P30 MH068638NIMH NIH HHS P30 MH085943NIMH NIH HHS R01 MH076829PHS HHS R01 HLB071992
6 · The paper itself

Abstract

Chronic obstructive pulmonary disease (COPD) is often complicated by depression and exemplifies the challenge in managing chronic illnesses that require active patient participation in care. In a clinical trial (NCT00151372), we compared a novel personalised intervention for depression and COPD (PID-C) targeting treatment adherence with treatment as usual (TAU). In 138 patients with major depression and severe COPD, PID-C led to a higher remission rate and a greater reduction in depressive symptoms and in dyspnoea-related disability than TAU over 28 weeks and 6 months after the last session. If replicated, PID-C may serve as a care model for patients with both depression and medical illnesses with a deteriorating course.

Indexed as

Health Knowledge, Attitudes, PracticeAdultDisease ProgressionDyspneaHumansIntention to Treat AnalysisMajor Depressive DisorderMonte Carlo MethodOutcome Assessment, Health CarePatient CompliancePsychiatric Status Rating ScalesPulmonary Disease, Chronic ObstructiveRemission InductionSurvival Analysis

Identifiers

PMID23391728
PMCPMC3585422
OpenAlexW2164066892

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.