Evidence map›Paper›PMID 23391504›Full record

ArticleArchives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists2013

Predictors of neuropsychological change in patients with chronic myelogenous leukemia and myelodysplastic syndrome.

Mary-Ellen Meadows, Grace Chang, Jennifer A Jones, Joseph R Antin, E John Orav

Abstract read
In one paragraph

Article in Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Survivorship: cognitive function, version 1.2014.Journal of the National Comprehensive Cancer Network : JNCCN · 2014
    Guideline
  2. Observational
  3. Article
  4. Review
  5. Article
  6. Prospective analysis of the attendance behaviour of the participants of a facilitated support group for patients after allogeneic hematopoietic cell transplantation.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mary-Ellen MeadowsDivision of Cognitive and Behavioral Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA. mmeadows@partners.org
Grace Chang
Jennifer A Jones
Joseph R Antin
E John Orav

Funding

Patients, Clinics, and Systems: Screening for Alcohol UseK24AA000289 · NIAAA · HARVARD MEDICAL SCHOOL · PI CHANG, GRACE · 1999 to 2010
$1.2M
NIAAA NIH HHS K24 AA 000289NIAAA NIH HHS K24 AA000289
6 · The paper itself

Abstract

This study examined the course of neuropsychological functioning in patients with chronic myelogeous leukemia (n = 91) or myelodysplastic syndrome (n = 15) who underwent standard treatment for their disease or allogeneic hematopoietic stem cell transplantation (HSCT) at baseline, 12 months, and 18 months post-treatment. At baseline, 23% of the participants (n = 75) in the longitudinal sample had Z-scores on at least one of the neuropsychological tests that were <1.4. Participants in the study showed improvement over baseline at the 12 and 18 months assessments. The average Z-scores for the six cognitive domains in the longitudinal data set over the course of the study ranged from -0.89 to 0.59. Significant predictors of change in neuropsychological test scores included age, with older participants showing less improvement over time. Other predictors included baseline cognitive domains (language, memory, and attention), previous cocaine use, disease status, intelligence quotient, and quality of life measures. Findings support previous studies in patients with hematological malignancies who showed cognitive impairments at baseline prior to HSCT. However, there was little evidence for further cognitive decline over the course of 18 months.

Indexed as

Neuropsychological TestsAdultCognition DisordersFemaleHematopoietic Stem Cell TransplantationHumansLeukemia, Myelogenous, Chronic, BCR-ABL PositiveLongitudinal StudiesMaleMiddle AgedMultivariate AnalysisMyelodysplastic SyndromesPredictive Value of TestsTime FactorsTreatment OutcomeCancerCancer treatmentCognitionHematological malignancyHematopoietic stem cell transplantationNeuropsychology

Identifiers

PMID23391504
PMCPMC3656510

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.