ArticleThe Journal of hand surgery2013
Supercharge nerve transfer to enhance motor recovery: a laboratory study.
Article in The Journal of hand surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 96 citations in OpenAlex.
- Supercharge End-to-Side Nerve Transfer: Systematic Review.Hand (New York, N.Y.) · 2021Pooled it
- Electrodiagnostic and Clinical Outcomes after Supercharged Anterior Interosseous Nerve Transfer in Advanced Cubital Tunnel Syndrome.Clinics in orthopedic surgery · 2026Article
- Motor Nerve Transfers in Complete and Incomplete Brachial Plexus Injuries: A State-of-the-Art Review.Neurology international · 2026Review
- Role of donor nerves in supercharge end-to-side nerve transfer: A rat model study of varying injury severity.PloS one · 2026Article
- Effect of end-to-side anterior interosseous nerve transfer in proximal ulnar nerve injuries: A comparative study.Journal of hand and microsurgery · 2025Article
- Assessment, management, and rehabilitation of traumatic peripheral nerve injuries for non-surgeons.Muscle & nerve · 2025Review
- The role of nerve transfers in chronic nerve compression syndromes.International orthopaedics · 2025Review
- Superficial peroneal to tibial nerve transfer for restoring plantar flexion in partial sciatic nerve injuries: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Axonal regeneration and innervation ratio following supercharged end-to-side nerve transfer.Frontiers in cell and developmental biology · 2025Article
- Anterior Interosseus to Ulnar Motor Nerve Transfers: A Canadian Perspective.Hand (New York, N.Y.) · 2024Article
- Outcomes of Nerve Transfers in Peroneal Nerve Palsy.Plastic surgery (Oakville, Ont.) · 2024Article
- Novel Method of Dual-innervated Free Gracilis Muscle Transfer for Facial Reanimation: A Case Series.Plastic and reconstructive surgery. Global open · 2023Article
- Assessment, patient selection, and rehabilitation of nerve transfers.Frontiers in rehabilitation sciences · 2023Review
- Application of Supercharge End-to-Side (SETS) Obturator to Femoral Nerve Transfer in Electrical Injury-Induced Neuropathy to Improve Knee Extension.Archives of plastic surgery · 2022Article
- Reverse End-to-Side (Supercharging) Nerve Transfer: Conceptualization, Validation, and Translation.Hand (New York, N.Y.) · 2022Review
- Review
- Lower Extremity Nerve Transfers in Acute Flaccid Myelitis Patients: A Case Series.Plastic and reconstructive surgery. Global open · 2021Article
- Neuroplasticity following Nerve Transfer of the Anterior Interosseous Nerve for Proximal Ulnar Nerve Injuries.Plastic and reconstructive surgery. Global open · 2021Article
- Trends in Nerve Transfer Procedures Among Board-Eligible Orthopedic Hand Surgeons.Journal of hand surgery global online · 2021Article
- Muscle-Nerve-Nerve Grafting Improves Facial Reanimation in Rats Following Facial Nerve Injury.Frontiers in neurology · 2021Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
purposeTo investigate the ability of a supercharge end-to-side (SETS) nerve transfer to augment the effect of regenerating native axons in an incomplete rodent sciatic nerve injury model.
methodsFifty-four Lewis rats were randomized to 3 groups. The first group was an incomplete recovery model (IRM) of the tibial nerve complemented with an SETS transfer from the peroneal nerve (SETS-IRM). The IRM consisted of tibial nerve transection and immediate repair using a 10-mm fresh tibial isograft to provide some, but incomplete, nerve recovery. The 2 control groups were IRM alone and SETS alone. Nerve histomorphometry, electron microscopy, retrograde labeling, and muscle force testing were performed.
resultsHistomorphometry of the distal tibial nerve showed significantly increased myelinated axonal counts in the SETS-IRM group compared with the IRM and SETS groups at 5 and 8 weeks. Retrograde labeling at 8 weeks confirmed increased motoneuron counts in the SETS-IRM group. Functional recovery at 8 weeks showed a significant increase in muscle-specific force in the SETS-IRM group compared with the IRM group.
conclusionsAn SETS transfer enhanced recovery from an incomplete nerve injury as determined by histomorphometry, motoneuron labeling within the spinal cord, and muscle force measurements. CLINICAL RELEVANCE: An SETS distal nerve transfer may be useful in nerve injuries with incomplete regeneration such as proximal Sunderland II- or III-degree injuries, in which long regeneration distance yields prolonged time to muscle reinnervation and suboptimal functional recovery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.