ArticleJournal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent2013
How does a Developmental Perspective inform us about the early Natural History of Bipolar Disorder?
Article in Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 22 citations in OpenAlex.
- Childhood trajectories of emotional and behavioral difficulties are related to polygenic liability for mood and anxiety disorders.Journal of child psychology and psychiatry, and allied disciplines · 2025Article
- Longitudinal studies of bipolar patients and their families: translating findings to advance individualized risk prediction, treatment and research.International journal of bipolar disorders · 2024Review
- Childhood Clinical Features Preceding the Onset of Bipolar Versus Major Depressive Disorders During Adolescence.Journal of attention disorders · 2024Article
- Familial load of psychiatric disorders and overall functioning in patients newly diagnosed with bipolar disorder and their unaffected first-degree relatives.International journal of bipolar disorders · 2022Article
- The Staging of Major Mood Disorders: Clinical and Neurobiological Correlates.Psychiatry investigation · 2018Article
- Do the Trajectories of Bipolar Disorder and Schizophrenia Follow a Universal Staging Model?Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2017Review
- An Exploration of Positive Parenting in Relation to Psychopathology for Youth with a Diagnosis of Bipolar Spectrum Disorder.Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent · 2017Article
- Assessment and Treatment of Bipolar Spectrum Disorders in Emerging Adulthood: Applying the Behavioral Approach System Hypersensitivity Model.Cognitive and behavioral practice · 2016Article
- Staging Models in Bipolar Disorder: A Systematic Review of the Literature.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2016Review
- Article
- Candidate Risks Indicators for Bipolar Disorder: Early Intervention Opportunities in High-Risk Youth.The international journal of neuropsychopharmacology · 2015Review
- Toward a comprehensive clinical staging model for bipolar disorder: integrating the evidence.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2014Review
- Developmental approaches to child psychopathology: longitudinal studies and implications for clinical practice.Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent · 2013Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe focus of this paper is to explore how a developmental perspective can advance understanding of the clinical trajectory into bipolar disorder (BD) and clarify controversies regarding the diagnosis in youth.
methodIn this selective review, we focus on findings from longitudinal studies of general population and high-risk pediatric cohorts in order to inform our understanding of the development of BD in youth. Also highlighted are related aspects of the debate about the diagnosis in young children and a discussion of the implications of the findings for advancing early detection and intervention clinical and research efforts.
resultsEvidence overwhelmingly suggests that BD typically onsets in adolescence and early adulthood, with the depressive polarity of the illness dominating the early course. Non-specific childhood antecedents have been noted in some high-risk individuals. However, in youth without a confirmed familial risk of BD, manic-like symptoms have little prognostic significance for BD and not uncommonly form part of the normative adolescent experience. Over-emphasis of symptoms and reliance on parent report alone, alongside the relative neglect of the child's developmental stage and risk profile, contributes to the over diagnosis in young children and under recognition of BD early in the clinical course.
conclusionsLongitudinal population and high-risk studies over development have made major contributions to our understanding of the early natural history of BD in youth. Implications call for a different diagnostic approach to facilitate accurate identification of youth in the early clinical stages of psychiatric disorders and to differentiate between the emerging illness trajectories and transient normative symptoms in childhood and adolescence.
Indexed as
Identifiers
23390427PMC3565709W1485361579What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.