Evidence map›Paper›PMID 23390299›Full record

ReviewThe Journal of infectious diseases2013

An epidemiologic update on hepatitis C infection in persons living with or at risk of HIV infection.

Arthur Y Kim, Shauna Onofrey, Daniel R Church

Open access · bronzeAbstract readReview
In one paragraph

Review in The Journal of infectious diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 1 pooled it
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 1 synthesis or guideline pooled it, 104 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  5. Observational
  6. Serum albumin and white matter hyperintensities.Translational psychiatry · 2024
    Article
  7. Review
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  11. Heterogeneity in Jail Nursing Medical Intake Forms: A Content Analysis.Journal of correctional health care : the official journal of the National Commission on Correctional Health Care · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Arthur Y KimDivision of Infectious Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. akim1@partners.org
Shauna Onofrey
Daniel R Church
Massachusetts Department of Public Health · USMassachusetts General Hospital · US

Funding

The role of NK cells during acute HCV infection and antiviral therapyU19AI066345 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI ALTER, GALIT · 2005 to 2014
$8.5M
Discovery and Assessment of Genetic Determinants of HCV and HIV ControlR01DA033541 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI CHUNG, RAYMOND T, KIM, ARTHUR Y · 2011 to 2015
$3.4M
International Collaborative of prospective studies of HIV and Hepatitis in IDUR01DA031056 · NIDA · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI PAGE, KIMBERLY · 2011 to 2015
$2.2M
Simulation Modeling to Improve HIV/HCV Screening, Treatment and CareR01DA031059 · NIDA · BOSTON MEDICAL CENTER · PI LINAS, BENJAMIN P. · 2012 to 2015
$2.1M
NIAID NIH HHS U19 AI066345NIDA NIH HHS R01 DA 031056NIDA NIH HHS R01 DA031056NIDA NIH HHS R01 DA 031059NIDA NIH HHS R01 DA031059NIDA NIH HHS R01 DA 033541NIDA NIH HHS R01 DA033541
6 · The paper itself

Abstract

Due to shared routes of transmission, coinfection with both human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV) is relatively common and results in accelerated liver disease, driving morbidity and mortality. Deaths related to HCV now exceed deaths related to HIV in the United States, and co-infected patients bear a significant proportion of that mortality. This burden may be addressed by novel antiviral therapies that promise increased rates of cure or by enhanced access to liver transplantation, but these are costly interventions. Ultimately, the future burden of coinfection is addressed by greater understanding of who is at risk for development of each infection, thus guiding preventive efforts. Key recent reports regarding the US burden of morbidity and mortality due to HCV and groups at risk for coinfection are reviewed, with a focus on recently described HCV occurring among young injection drug users and men who have sex with men. Given the lack of available vaccine against HCV, enhanced detection and surveillance is a vital component of our public health strategy to combat HCV.

Indexed as

Antiviral AgentsCoinfectionFemaleHepatitis CHIV-1HIV InfectionsHumansLiver TransplantationMaleRisk FactorsSurvival AnalysisUnited StatesAntiviral Agents

Identifiers

PMID23390299
PMCPMC3565593
OpenAlexW2158733025

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.