Evidence map›Paper›PMID 23390288›Full record

ArticleJournal of clinical microbiology2013

Quantification of viral loads lower than 50 copies per milliliter by use of the Cobas AmpliPrep/Cobas TaqMan HIV-1 test, version 2.0, can predict the likelihood of subsequent virological rebound to >50 copies per milliliter.

Marta Álvarez Estévez, Natalia Chueca Porcuna, Vicente Guillot Suay, Alejandro Peña Monge, Fernando García García, Leopoldo Muñoz Medina, David Vinuesa García, Jorge Parra Ruiz, Jose Hernández-Quero, Federico García García

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  13. Characterizing Patients with Very-Low-Level HIV Viremia: A Community-Based Study.Journal of the International Association of Providers of AIDS Care
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Marta Álvarez EstévezMicrobiology Service, Hospital Universitario San Cecilio, Granada, Spain.
Natalia Chueca Porcuna
Vicente Guillot Suay
Alejandro Peña Monge
Fernando García García
Leopoldo Muñoz Medina
David Vinuesa García
Jorge Parra Ruiz
Jose Hernández-Quero
Federico García García

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

After 1 year of follow-up, patients on HAART with a baseline viral load (VL) of <20 copies/ml showed significantly lower odds of virological rebound to two consecutive VLs of >50 copies/ml than those with baseline VLs of 20 to 39 and 40 to 49 (P < 0.001). The time to virological rebound was also significantly shorter (P < 0.001) for the groups with baseline VLs of 20 to 39 and 40 to 49.

Indexed as

Viral LoadAdultAntiretroviral Therapy, Highly ActiveFemaleHIV-1HIV InfectionsHumansMaleMiddle AgedPrognosisRecurrenceRNA, ViralViremiaRNA, Viral

Identifiers

PMID23390288
PMCPMC3647906

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.